Zoledronic Acid
Zoledronic Acid Information

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Zoledronic Acid

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About Zoledronic Acid

A bisphosphonate, which affects bone metabolism. It is adsorbed onto hydroxyapetite cryastals in bone , slowing both their rate of growth and dissolution, and therefore reducing the rate of bone turnover. It reduces bone damage in advanced malignancies involving bone (with calcium and vitamin D supplement), it is also given in hypercalcemia of malignancy.

Indications

Zoledronic Acid is primarily indicated in conditions like Hypercalcaemia of malignancy, Reduction of bone damage, Skeletal disorder prevention in bone malignancies, Tumour induced hypercalcaemia.

Contraindication

Zoledronic Acid is contraindicated in conditions like Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Zoledronic Acid, which give rise to further complications include Anemia, Bradycardia, Renal impairment, Increased creatinine, Increase in blood urea, Hypoglycemia.The symptomatic adverse reactions produced by Zoledronic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Headache, Fatigue, Nausea, Vomiting, Anorexia, Fever, Myalgia, Bone pain, Arthralgia, Taste perversion, Conjunctivitis.

Warnings

No data regarding the Warnings/Precuations of Zoledronic Acid is available.

High Risk Groups

Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage


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