Yohimbine (HCl)
Yohimbine (HCl) Information

About Yohimbine (HCl)

An indole alkaloid, is an alpha-2 selective antagonist. It has no established clinical role. Theoretically, it could be useful in autonomic insufficiency by promoting neurotransmitter release through blockade of presynaptic alpha-2 receptors.

Indications

Yohimbine (HCl) is primarily indicated in conditions like Organic and psychosomatic impotance, Orthostatic hypotension, and can also be given in adjunctive therapy as an alternative drug of choice in Obesity.

Contraindication

Yohimbine (HCl) is contraindicated in conditions like Renal diseases.

Side Effects

The severe or irreversible adverse effects of Yohimbine (HCl), which give rise to further complications include Atrial fibrillation, Loss of memory.Yohimbine (HCl) produces potentially life-threatening effects which include Tachycardia, Cardiac arrhythmia, Hypertension. which are responsible for the discontinuation of Yohimbine (HCl) therapy.The signs and symptoms that are produced after the acute overdosage of Yohimbine (HCl) include Nausea, Tachycardia, Palpitations, Headache, Hypertension, Paresthesia, Teichopsia, Anxiety, Weakness, Chest pain.The symptomatic adverse reactions produced by Yohimbine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Increased BP, Paresthesias, Incoordination, Increased heart rate, Rhinorrhea, Increased salivation.

Warnings

High Risk Groups

Drug should not be given to Paediatrics, Cardiac / Hypertensive Patients, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.