Varicella Virus Vaccine
Varicella Virus Vaccine Information

About Varicella Virus Vaccine

A freeze-dried preparation of the attenuated strains of Herpesvirus varicellae grown in cultures of human diploid cells. It is used for active immunization against varicella (chickenpox) in persons considered to be at high risk of either contracting the infection or to be highly susceptible to any complications it may cause.

Indications

Varicella Vaccine is primarily indicated in conditions like Varicella prophylaxis.

Contraindication

Varicella Vaccine is contraindicated in conditions like Leukaemia,Bone marrow depression,Infections,Tuberculosis,AIDS,Neoplastic disease,Respiratory infection,Febrile illness,Immunosuppression.

Side Effects

The severe or irreversible adverse effects of Varicella Vaccine, which give rise to further complications include Skin rashes, Anaphylactic reactions, Breathing difficulty, Hives, Face and eyes swelling.The symptomatic adverse reactions produced by Varicella Vaccine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Tiredness, Headache, Fatigue, Irritability, Diarrhea, Fever, Nervousness, Pain, Cough, Muscle aching, Paresthesias, Disturbed sleep, Reaction at injection site, Papular vesicular eruption.

Warnings

Immunosuppressive therapy can cause a more extensive reaction to a live vaccine therefore immuno suppression contraindicates the use of varicella vaccine. It is advisable not to give varicella vaccine to any patient who has received blood or plasma transfusions within the previous 5 months. Patient with leukemia, neoplastic disease or any blood dyscrasia should not recieve the vaccine. Because of the chances of anaphylactic reactions the vaccinee should remain in under medical supervision for 30 minutes after immunization. Varicella vaccine contains trace amounts of neomycin and should not be given to anyone with a history of neomycin hypersensitivity. Patients with a history of hypersensitivity to any component of the vaccine, including gelatin, should not receive varicella vaccine. It is recommended that varicella vaccine is not administered either during pregnancy, or within the three months before becoming pregnant. Vaccine should be used with caution in breast-feeding women. There is also a possibility of transmitting the virus from a newly vaccinated individual to other persons. Varcellia vaccine should not be administered intradermally and must under no circumtances be administered intravenously.In high risk patients varicellia vaccine should not be administered at the same time as other live attenuated vaccines.

High Risk Groups

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.