Tranexamic Acid
Tranexamic Acid Information

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Tranexamic Acid

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About Tranexamic Acid

Tranexamic Acid is antifibrinolytic agent. Tranexamic Acid is analogue of aminocaproic acid. Chemically Tranexamic Acid is identified as trans-4-(aminomethyl) cyclohexanecarboxylic acid. Tranexamic Acid is effective to reversed the effects of streptokinase or other fibrinolytic activity. It may be used for conditions in which bleeding control is required such as after surgery or injury, recurrent nosebleeds or abnormal vaginal bleeding.

Indications

Tranexamic Acid is primarily indicated in conditions like Acute spasm and spasm in diagnostic procedures, Angioneurotic edema, Haemophilia, Prevention of bleeding, Subarachnoid haemorrhage, and can also be given in adjunctive therapy as an alternative drug of choice in Epistaxis, GI hemorrhage, Menorrhagia.

Contraindication

Tranexamic Acid is contraindicated in conditions like Thrombosis,Renal diseases,Color blindness,Hematuria.

Side Effects

The severe or irreversible adverse effects of Tranexamic Acid, which give rise to further complications include Acute renal failure, Myopathy.Tranexamic Acid produces potentially life-threatening effects which include Intracranial thrombosis. which are responsible for the discontinuation of Tranexamic Acid therapy.The symptomatic adverse reactions produced by Tranexamic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Rashes, Purpura.

Warnings

Dose of tranexamic acid should be reduced in patients of renal (kidney) insufficiency because of accumulation.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Tranexamic Acid Dosage for Adults

Dose 250 to 750 mg
Single Dose 500 (500)
Frequency 8 hourly
Route PO
Dose 0.5 to 1 g
Single Dose 0.75 (0.75)
Frequency 8 hourly
Route Slow IV
Note: Local fibrinolysis

Tranexamic Acid Dosage for Neonatal

Dose 25 mg/kg
Single Dose 25 (25)
Frequency 8 hourly
Route Oral
Note: -

Tranexamic Acid Dosage for Paedriatic

Dose 25 mg/kg
Single Dose 25 (25)
Frequency 8 hourly
Route Oral
Note: -

Brands


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