Tramadol (HCl)
Tramadol (HCl) Information
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Tramadol (HCl)
medicine,pricing, side effects of Tramadol (HCl) medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Tramadol (HCl)
Tramadol (HCl) is a centrally-acting analgesic with a unique, dual mechanism of action, within the CNS; it exerts agonistic properties at opiate receptors and interferes with neurotransmitter reuptake.Tramadol also binds weakly to µ-opiate receptors blocking the transmission of pain signals to the brain. It was originally thought that the drug had negligible abuse potential, but after its marketing, reports of drug abuse and withdrawal have been noted. The WHO guidelines indicate there is a place for tramadol in controlling moderate, but not severe, cancer pain.Tramadol has been effective in the control of post-operative pain, but is not suitable as an adjunct to anesthesia because of low sedative properties. Comparative studies with other analgesics for the treatment of postoperative pain indicate that tramadol is equivalent in potency to meperidine, one fifth as potent as nalbuphine, and one thousandth as potent as fentanyl. Respiratory depression caused by tramadol is less than that caused by morphine or meperidine but is apparent after overdose.
Indications
Tramadol (HCl) is primarily indicated in conditions like Moderate to severe pain, Pain, Parkinson's disease; drug-induced extrapyramidal symptoms.
Contraindication
Tramadol (HCl) is contraindicated in conditions like Respiratory disease,Unconciousness,Acne rosacea.
Side Effects
The severe or irreversible adverse effects of Tramadol (HCl), which give rise to further complications include Seizures, Physical dependence.The signs and symptoms that are produced after the acute overdosage of Tramadol (HCl) include Coma, Respiratory depression, Respiratory depression, Shock.The symptomatic adverse reactions produced by Tramadol (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Restlessness, Constipation, Dry mouth, Pruritus, SomnolenceX, Bronchospasm, Angioedema.
Warnings
Tramadol should be used with caution in patients with pre-existing kidney disease, liver disease, seizure disorder, lungs disease, history of drug dependency or have any allergy. It should be used with caution during pregnancy or lactation.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Tramadol (HCl) Dosage for Adults
| Dose | 50 to 100 mg |
| Single Dose | 75 (75) |
| Frequency | 6 hourly |
| Route | PO,IV,IM |
| Note: maximun oral dose is 400mg, IV injection given over 2 to 3min | |
| Dose | 100 mg |
| Single Dose | 100 (100) |
| Frequency | 4 hourly |
| Route | Rectal |
| Note: maximun oral dose is 400mg, IV injection given over 2 to 3min |
Tramadol (HCl) Dosage for Neonatal
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Intra Muscular |
| Note: - | |
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Oral |
| Note: - | |
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Slow IV |
| Note: - |
Tramadol (HCl) Dosage for Paedriatic
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Intra Muscular |
| Note: - | |
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Oral |
| Note: - | |
| Dose | 1 to 2.5 mg/kg |
| Single Dose | 1.8 (1.75) |
| Frequency | 8 hourly |
| Route | Slow IV |
| Note: - |
Brands
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