Tobramycin
Tobramycin Information

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Tobramycin

medicine,pricing, side effects of Tobramycin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Tobramycin

Tobramycin is an aminoglycoside antibiotic derived from a complex produced by Streptomyces tenebrarius. The aminoglycosides are the compound containing characteristic amino sugars joined to a hexose nucleus in glycoside linkage. Aminoglycosides are polycations and their polarity accounts for their pharmakokinetic peopertie. Tobramycin is effective against a wide range of aerobic gram negative bacilli and some gram positive bacteria. Tobramycin is used in the treatment of septicemia caused by gram -ve organism, respiratory infections, urinary tract infections, CNS infection. Tobramycin is given topically as eye drops to treat Pseudomonas eye infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular intervel of time throughout the day and night as prescribed. Tobramycin is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.

Indications

Tobramycin is primarily indicated in conditions like Bacterial infections, Biliary tract infections, Chronic pulmonary pseudomonas aeruginosa infection in cystic fibrosis patients, Cystic fibrosis, Endocarditis, Eye infections, Gram +ve (some) and gram -ve (many) infections, Heart failure, Iron deficiency anaemia, NSAID-associated ulceration, Oliguria due to renal failure, Pneumonia in hospital patients, Prohylaxis of stress ulceration, Respiratory tract infections, Septicaemia, Supraventricular arrhythmias (particularly atrial fibrillation), Symptoms associated with carcinoid tumours, Trauma, Ulcerative colitis and crohn's disease, Urinary tract infection, UTI.

Contraindication

Tobramycin is contraindicated in conditions like Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Tobramycin, which give rise to further complications include Ototoxicity, Elevation in serum creatinine, Neuromuscular blockage.Tobramycin produces potentially life-threatening effects which include Nephrotoxicity, Dehydration, Proteinuria, Oliguria, Hyperuricemia. which are responsible for the discontinuation of Tobramycin therapy.The symptomatic adverse reactions produced by Tobramycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Maculopapular rash, Urticaria, Local pain, Phlebitis.

Warnings

Tobramycin should be used with caution in patients with history of kidney diseases, vertigo, hearing loss, myasthenia gravis, parkinsonisms. It should be used with caution in patients who are sensitive to aminoglycosides. Perform monthly blood counts test for atleast 4 months. Keep patients well hydrated to prevent chemical irritation or nephrotoxic reactions. Take appropriate measures in case of secondary infections.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Tobramycin Dosage for Adults

Dose 3 to 5 mg/ kg
Single Dose 4 (4)
Frequency As recommended.
Route IM,Slow IV
Note: In 3-4 divided doses.
Dose 0.3 % w/v
Single Dose 0.3 (0.3)
Frequency 6 hourly
Route Ophthalmic, Otic

Tobramycin Dosage for Neonatal

Dose 2 to 2.5 mg/kg
Single Dose 2.2 (2.25)
Frequency 8 hourly
Route Intra Muscular
Note: -
Dose 2 to 2.5 mg/kg
Single Dose 2.2 (2.25)
Frequency 8 hourly
Route Intra Venous
Note: -

Tobramycin Dosage for Paedriatic

Dose 2 to 2.5 mg/kg
Single Dose 2.2 (2.25)
Frequency 8 hourly
Route Intra Muscular
Note: -
Dose 2 to 2.5 mg/kg
Single Dose 2.2 (2.25)
Frequency 8 hourly
Route Intra Venous
Note: -

Brands

1- ABBOCIN - 20mg MG

2- ABBOCIN - 80mg MG

3- AMGY - 0.3%w/v MG

4- AMGYDEX - 0.3%w/v MG

5- AMGYDEX - 0.3%w/w MG

6- BRACIN - 0.3%w/v MG

7- BRACIN - 0.3%w/w MG

8- BRACIN-D - 0.3%w/v MG

9- BRADEX - 0.3%w/v MG

10- BROMOREX - 0.3%w/v MG

11- BROMOREX - 0.3%w/w MG

12- BROMOREX - 20mg MG

13- BROMOREX - 80mg MG

14- BROMYCIN - 0.3%w/v MG

15- BROMYCIN - 0.3%w/w MG

16- BROMYCIN-D - 0.3%w/v MG

17- BRULACIL - 0.3%w/v MG

18- BRULACIL - 20mg MG

19- BRULACIL - 20mg MG

20- BRULACIL - 20mg MG

21- BRULAMYCIN - 0.3%w/v MG

22- BRULAMYCIN - 20mg MG

23- CINDEX - 0.3%w/v MG

24- DEXADRON T - 0.3%w/v MG

25- DEXATOB - 0.3%w/v MG

26- DICON EYE DROPS - 0.3%w/v MG

27- EYEBRADEX - 0.3%w/v MG

28- EYEBREX - 0.3%w/v MG

29- EYEBREX - 0.3%w/w MG

30- KLOZEN - 0.3%w/v MG

31- LOTEPRED-T - 0.3%w/v MG

32- MAGRACIN - 20mg MG

33- MEBRADEX - 0.3%w/v MG

34- MINOSIDE - 0 MG

35- MORCIN - 0.3%w/v MG

36- MQOBRA - 0 MG

37- MYDEX - 0.3%w/v MG

38- MYNOSIDE - 3%w/v MG

39- MYNOSIDE - 20mg MG

40- MYNOSIDE - 80mg MG

41- MYRET - 0.3%w/v MG

42- MYTOBRA - 20mg MG

43- NABROD - 40mg MG

44- NABROD - 20mg MG

45- NABROD - 80mg MG

46- NEBCIN - 20mg MG

47- NEBCIN - 10mg MG

48- NEBCIN - 80mg MG

49- NEBCIN - 10mg MG

50- NEBRA - 0.3%w/v MG

51- NEBRA - 0.3%w/w MG

52- NEO-BREX - 0.3%w/v MG

53- NEO-BREX - 0.3%w/w MG

54- OBRADEX - 0.3%w/v MG

55- OBRAMYCIN - 20mg MG

56- OBRAMYCIN - 80mg MG

57- OBREX - 0.3%w/v MG

58- OCUCID - 0 MG

59- OCUTOB - 0 MG

60- OCUTOB-DEX - 0.3%w/v MG

61- OCUTODEX - 0 MG

62- OPHTH-TOBRA - 0.3%w/v MG

63- OPHTH-TOBRA-D - 0.3%w/v MG

64- OPHTH-TOBRA-D - 0.3%w/w MG

65- OPTIBRAM - 0.3%w/v MG

66- ORBACIN - 0.3%w/v MG

67- ORCY - 0 MG

68- ORCYDEX - 0 MG

69- OTOTOB - 0.3%w/v MG

70- REVICURE - 0.3%w/v MG

71- SANTOBREX - 0.3%w/v MG

72- SANTOBREX - 0.3%w/w MG

73- SANTODEX - 0.3%w/v MG

74- SANTODEX - 0.3%w/w MG

75- TOBCIN - 0.3%w/v MG

76- TOBCIN - 20mg MG

77- TOBCIN - 80mg MG

78- TOBCY - 0.3% w/v MG

79- TOBCY - 0.3% w/w MG

80- TOBCYDEX - 0.35% MG

81- TOBRA - 0.3%w/v MG

82- TOBRA-D - 0.3%w/v MG

83- TOBRACIN - 0.3%w/v MG

84- TOBRACIN INJ - 20mg MG

85- TOBRACIN INJ - 80mg MG

86- TOBRACIN-D - 0.3%w/v MG

87- TOBRADEX - 0.3%w/v MG

88- TOBRADEX - 0.3%w/w MG

89- TOBRADON - 20mg MG

90- TOBRADON - 80mg MG

91- TOBRAMET - 0.3%w/v MG

92- TOBRASONE - 0.3%w/v MG

93- TOBRAXIA - 0.3%w/v MG

94- TOBREX - 0.3%w/v MG

95- TOBREX - 0.3%w/w MG

96- TOBRIN - 20mg MG

97- TOCIN - 20mg MG

98- TOCIN - 80mg MG

99- TODEX - 0.3%w/v MG

100- TOMA - 0.3%w/v MG

101- TRANCE - 0.3%w/v MG

102- VEGATOB - 0 MG


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