Thyroxine (Na)
Thyroxine (Na) Information

About Thyroxine (Na)

Thyroxine (Na) is the major hormone elaborated by the thyroid gland. Chemically itL-3, 5, 3', 5'-tetraiodothyronine. it's chief function is to increase the rate of cell metabolism. italso essential for the central nervous system maturation and regulates a number of other functions. itmainly used in the treatment of hypothyroidism.

Indications

Thyroxine (Na) is primarily indicated in conditions like Acquired hypothyroidism, Congenital hypothyroidism, Cretinism, Hypothyroidism, Myxedema coma, Non-toxic goiter.

Contraindication

Thyroxine (Na) is contraindicated in conditions like Angina,Cardiac failure,Pituitary disease,Adrenal failure.

Side Effects

The severe or irreversible adverse effects of Thyroxine (Na), which give rise to further complications include Sinus tachycardia, Diarrhoea, Tachycardia, Cardiac arrhythmias, Insomnia, Weight loss, Agitation, Tremors, Heat intolerance.Thyroxine (Na) produces potentially life-threatening effects which include Myocardial infarction, Exacerbation of angina, Exacerbation of cardiac arrhythmias. which are responsible for the discontinuation of Thyroxine (Na) therapy.The signs and symptoms that are produced after the acute overdosage of Thyroxine (Na) include Coma, Hyperpyrexia, Cardiovascular collapse, Thyrotoxicosis.The symptomatic adverse reactions produced by Thyroxine (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Alopecia, Anorexia, Diaphoresis, Amenorrhea, Atrial fibrillation.

Warnings

Thyroxine should be used with caution in patients with heart problems, diabetes, adrenal gland problems or of any allergy, including drug allergies. Avoid using thyroid drugs for weight control. Current information shows that this drug may be used during pregnancy. It should be used with caution during lactation.

High Risk Groups

Drug should not be given to Paediatrics, Cardiac / Hypertensive Patients, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.