Thymosin alpha one
Thymosin alpha one Information
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Thymosin alpha one
medicine,pricing, side effects of Thymosin alpha one medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Thymosin alpha one
Thymosin alpha-1 (TA1) is an investigational drug in Phase II trials for the treatment of chronic hepatitis B and in Phase III trials for the treatment of chronic hepatitis C. Phase II trials for hepatocellular carcinoma, malignant melanoma, and drug-resistant tuberculosis were scheduled to begin in fall 2000 (R. Koh, SciClone Pharmaceuticals, personal communication, 2000 May 5). TA1 has been granted orphan drug status for the treatment of chronic hepatitis B, HIV, hepatocellular carcinoma, and DiGeorge's syndrome with immune defects. (Di George's syndrome is a congenital birth defect that leads to hypoplasia or aplasia of the thymus and parathyroid glands, cardiac defects, and immune system dysfunction).
Indications
Thymosin alpha one is primarily indicated in conditions like AIDS, Chronic hepatitis B infection, DiGeorge's syndrome, Hepatitis C, Lung cancer, Malignant melanoma.
Contraindication
Thymosin alpha one is contraindicated in conditions like Hypersensitivity to any component of product.
Side Effects
The signs and symptoms that are produced after the acute overdosage of Thymosin alpha one include Nausea, Vomiting, fatigue, Muscle aches, Fever, Neutropenia.
Warnings
Thymosin comes as two doses in one small bottle. Once mixed with sterile water, the SECOND dose must be taken with TWO DAYS, or the drug will become too weak to be useful.TA1(Thymosin Alpha 1) is classified as being in pregnancy category C. Teratogenicity studies in both mice and rabbits have not demonstrated any difference when comparing TA1-treated and control animals. However, there are no data on TA1 in pregnant or nursing women. It is recommended that caution be exercised when administering the drug to nursing mothers.
High Risk Groups
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Thymosin alpha one Dosage for Adults
| Dose | 1 mg |
| Single Dose | 1 (1) |
| Frequency | As recommended. |
| Route | IM,SC |
| Note: twice a week. (This dose is used in clinical trials for HIV/AIDS.) | |
| Dose | 1 to 1.6 mg |
| Single Dose | 1.3 (1.3) |
| Frequency | As recommended. |
| Route | SC |
| Note: Twice a week either as monotherapy or in combination with interferon, in the treatment of chronic hepatitis B and C. When patients weigh less than 40 kg, TA1 should be given at a dose of 40 µg/kg. Once mixed, thymosin is only stable for two days. Suggested dosing schedule: Monday-Thursday or Tuesday-Friday. Keep it refrigerated at all times. |
Brands
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