Testosterone (Esters)
Testosterone (Esters) Information

About Testosterone (Esters)

Testosterone is the primary androgen found in the body. Endogenous testosterone is synthesized by cells in the testis, ovary, and adrenal cortex. Therapeutically, testosterone is used in the management of hypogonadism, either congenital or acquired. Testosterone is also the most effective exogenous androgen for the palliative treatment of carcinoma of the breast in postmenopausal women. Testosterone (Esters) is also used to treat menstrual disorder, breast cancer, postpartum breast pain and for suppression of lactation.

Indications

Testosterone (Esters) is primarily indicated in conditions like Androgen deficiency, Breast cancer, Hormone replacement therapy, Infertility, Menopausal symptoms, Micropenis, Muscle weakness.

Contraindication

Testosterone (Esters) is contraindicated in conditions like Heart failure,Prostatic cancer,Pregnancy.

Side Effects

The severe or irreversible adverse effects of Testosterone (Esters), which give rise to further complications include Skin rashes, Masculinization, Breathing difficulty.Testosterone (Esters) produces potentially life-threatening effects which include Hepatic carcinoma. which are responsible for the discontinuation of Testosterone (Esters) therapy.The signs and symptoms that are produced after the acute overdosage of Testosterone (Esters) include Fluid retension, Polycythemia, Anxiety.The symptomatic adverse reactions produced by Testosterone (Esters) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Vomiting, Jaundice, Depression, Sleeplessness, Edema, Acne, Gynecomastia, Decline in testis size, Supression of spermatogenesis, GI disorders.

Warnings

Testosterone should be used with caution in patients with any disease, especially cancer of the prostate or breast, liver, heart, kidney disease, allergy, enlarged prostate. High dosage, long term use of androgens has been related to liver cancer. This drug should not be used during pregnancy or lactation. Females should be monitored for signs of virilization, such as deepening of the voice, facial hair, acne, menstrual irregularity or clitoral enlargement, consult the doctor promptly if any of these symptoms occur. Use in children should not be recommended due to the possibility this drug may have undesirable effects related to the growth of the child. It should be use with extreme caution in geriatric men because they are at higher risk for developing enlarged prostates or prostate cancer when using this medication.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.