Sodium Stibogluconate
Sodium Stibogluconate Information

About Sodium Stibogluconate

Sodium Stibogluconate is antiprotozoal, used in the treatment of all types of leishmaniasis along with other drugs (eg; pentamidine and amphotericin B).

Indications

Sodium Stibogluconate is primarily indicated in conditions like Leishmaniasis, Visceral leishmaniasis.

Contraindication

Sodium Stibogluconate is contraindicated in conditions like Renal diseases,Pneumonia,Liver diseases,Heart disease,Complicating secondary infection,Previous antimonial therapy.

Side Effects

The severe or irreversible adverse effects of Sodium Stibogluconate, which give rise to further complications include Venous thrombosis.Sodium Stibogluconate produces potentially life-threatening effects which include Hepatotoxicity, Cardiotoxicity, Renal toxicity. which are responsible for the discontinuation of Sodium Stibogluconate therapy.The signs and symptoms that are produced after the acute overdosage of Sodium Stibogluconate include Renal failure, Circulatory collapse, Disseminated intravascular coagulopathy.The symptomatic adverse reactions produced by Sodium Stibogluconate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anorexia, Myalgia, Malaise, Arthralgia, Nausea and vomiting.

Warnings

Safety of the sodium stibogluconate has not been determined in pregnant women , in the children

High Risk Groups

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.