Sodium Fluoride
Sodium Fluoride Information

About Sodium Fluoride

A dental caries prophylactic. Sodium Fluoride is used as an adjunct to diet and oral hygiene Sodium Fluoride is used in the flouridation of water and applied topically to the teeth. It may render the enamel of the teeth more resistant to acid, promote remineralization, or reduce microbial acid production.

Indications

Sodium Fluoride is primarily indicated in conditions like A variety of solid tumors, Acute leukemia, Chronic lymphocytic leukaemia, Lymphomas.

Contraindication

Sodium Fluoride is contraindicated in conditions like Neonates.

Side Effects

The signs and symptoms that are produced after the acute overdosage of Sodium Fluoride include Cardiac arrhythmias, Convulsions, Respiratory arrest, Tremor, Shock, Paresthesia, Hyperreflexia, Cardiac failure, Hyperkalemia, Hypocalcemia, Tetany.The symptomatic adverse reactions produced by Sodium Fluoride are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Rashes, Hypersensitivity reactions.

Warnings

When consideration fluoride supplimentation, allowance should be made for fluorides ingested from other sources; fluoride sduppliments in children are not generally recommended when the fluoride content of drinking water is over 0.7 ppm (0.6 ppm in USA). Care should be taken to prevent children swallowing excessive fluoride after topical application to teeth. Patients with impaired renal function may be perticularly susceptible to fluorosis. Regular dialysis with fluoridated water may result in additional fluoride absorption; a maximum concentration of 0.2 ppm of fluoride in in the dialysate has been recommended. Dialysis patients not using deionised water are at risk from changes in the fluoride content of the water supply.

High Risk Groups

Drug should not be given to Paediatrics, Cardiac / Hypertensive Patients, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.