Sodium Biphosphate
Sodium Biphosphate Information

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Sodium Biphosphate

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About Sodium Biphosphate

Sodium Biphosphate is used in the management of hypophosphatemia caused by phosphate deficiency or hypophosphatemic states. Sodium Biphosphate is usually given orally, intravenous route is seldom necessary. It has also been employed for the prophylaxis of calcium renal calculi.

Indications

Sodium Biphosphate is primarily indicated in conditions like Analgesia and suppression of respiratory activity, Analgesia during operation, enhancement of anaesthesia, Hypercalcaemia.

Contraindication

Sodium Biphosphate is contraindicated in conditions like Hypersensitivity to any component of product.

Side Effects

The symptomatic adverse reactions produced by Sodium Biphosphate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypocalcemia, Hyperphosphatemia, Electrolyte imbalance.

Warnings

Phosphate should not generally be administered to patients with severe renal impairment. They should be avoided in patients who may have low-serum concentrations, as these may be decrease further, and in patients with infected phosphate renal calculi. Sodium Phosphate should generally be avoided in patients with congestive heart faliure (CHF), hypertension, and oedema. Serum electrolyte and renal function should be monitored during therapy, particularly if phosphates are administered parenterally. Oral or rectal sodium phosphate preparation should not be used in patients with gastro-intestinal obstruction, inflammatory bowel disease, and conditions where there is likely to be increased colonic absorption. They should be used with caution in elderly and debilitated patients, and in those with pre-existing electrolyte disturbances.

High Risk Groups

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage


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