Selegiline (HCl)
Selegiline (HCl) Information

About Selegiline (HCl)

Selegiline (HCl) is a selective inhibitor of monoamine oxidase B. Selegiline (HCl) is used along with levodopa in the management of Parkinson's disease. It inhibits the breakdown of dopamine in the brain and prolongs the action of Levodopa

Indications

Selegiline (HCl) is primarily indicated in conditions like Parkinsonism, Parkinson's disease, Parkinson's disease or symptomatic parkinsonism.

Contraindication

Selegiline (HCl) is contraindicated in conditions like Psychosis,Extrapyramidal disorders,Tardive dyskinesias,Huntington's disease.

Side Effects

The symptomatic adverse reactions produced by Selegiline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Diarrhea, Palpitation, Abdominal pain, Confusion, Malaise, Weight loss, Anemia, Dyskinesia, Urinary retention.

Warnings

Selegiline should be used with caution in patients with peptic ulcer and of allergies, especially of drug allergies. Rarely, this can cause headache and increased blood pressure when tyramine containing foods are ingested, consult the doctor about the use of diet containing tyramine (e.g.meat, fish, pickle, liver, dry sausage, meat prepared with tenderizer, yogurt, cheese, beverages, cheery, excessive amounts of caffeine, bananas, figs, raisins, broad beans, soy sauce, chocolate). Caution regarding food should be continued at least 2 weeks after discontinuing use of this drug. This drug should be used during pregnancy only if clearly needed.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.