Rifampicin
Rifampicin Information
Find all the information of Rifampicin medicine and drugs available in Pakistan. Read the pricing, side effects, usage, instructions and dosage of Rifampicin by .
Rifampicin
medicine,pricing, side effects of Rifampicin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Rifampicin
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation reaction between 3-formylrifamycin SV and 1-amino 4-methylpiperazine. Most gram positive and many gram negative bacteria are sensitive to it. itthe major drug in the treatment of tuberculosis. iteffective in combination with ethambutol, isoniazide, streptomycin and the majority of second line drugs.
Indications
Rifampicin is primarily indicated in conditions like Epilepsy (monotherapy), Iron-deficiency anaemia with chronic renal failure, Leprosy, Meningitis, Meningitis prophylaxis, Mycobacterial infection, Paget's disease of bone, Tuberculosis, Urinary tract infection, and can also be given in adjunctive therapy as an alternative drug of choice in Brucellosis, Endocarditis, Gonorrhoea, Legionnaires' disease.
Contraindication
Rifampicin is contraindicated in conditions like Hepatic disease,Jaundice.
Side Effects
The severe or irreversible adverse effects of Rifampicin, which give rise to further complications include Thrombocytopenic purpura, Flu-like syndrome.Rifampicin produces potentially life-threatening effects which include Sensitization, Shock- like syndrome. which are responsible for the discontinuation of Rifampicin therapy.The signs and symptoms that are produced after the acute overdosage of Rifampicin include Edema, Cardiovascular collapse, Nausea & vomiting, Pruritus, Red Man syndrome, Cutaneous pigmentation.The symptomatic adverse reactions produced by Rifampicin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Anorexia, Abdominal discomfort, Orange coloration of secretions.
Warnings
Rifampicin should be used during pregnancy or lactation only if clearly needed.Alcohol can reduce the effectiveness of this medication and increase side effects. Minimize alcohol consumption while taking rifampacin.Rifampacin can decrease the effectiveness of oral contraceptives. It should be used with caution in patients with liver problems.
High Risk Groups
Drug should not be given to patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Rifampicin Dosage for Adults
| Dose | 450 to 600 mg |
| Single Dose | 520 (525) |
| Frequency | As recommended. |
| Route | PO |
| Note: In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication. |
Rifampicin Dosage for Neonatal
| Dose | 10 to 20 mg/kg |
| Single Dose | 15 (15) |
| Frequency | 24 hourly |
| Route | Oral |
Rifampicin Dosage for Paedriatic
| Dose | 10 to 20 mg/kg |
| Single Dose | 15 (15) |
| Frequency | 24 hourly |
| Route | Oral |
| Note: Max 60mg/day |
Brands
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