Plasma Protein Fraction
Plasma Protein Fraction Information

About Plasma Protein Fraction

Plasma Protein Fraction is a sterile solution of selected proteins derived from the blood plasma of adult human donors. It contains protein, of which about 83-90% is albumin and the remainder is a and ß globulins. Plasma Protein Fraction is used as a substitute for plasma in treating non-hemorrhagic shock and as a source of protien for intravenous nutrition.

Indications

Plasma Protein Fraction is primarily indicated in conditions like Hypovolaemia, and can also be given in adjunctive therapy as an alternative drug of choice in Cardiac insufficiency.

Contraindication

Plasma Protein Fraction is contraindicated in conditions like Anaemia,Congestive heart failure,Hypersensitivity to any component of product.

Side Effects

The symptomatic adverse reactions produced by Plasma Protein Fraction are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Urticaria, Hypotension, Flushing, Back pain.

Warnings

Rapid infusion of Plasma Protein Fraction (greater than 10mL/minute) has produced hypotension in patients undergoing surgery or in the preoperative or postoperative period. Blood pressure should be monitored during use and infusion slowed or ceased if sudden hypotension occurs. Plasma Protein Fraction does not provide coagulation factors and therefore does not correct coagulation disorders.

High Risk Groups

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.