Pentoxifylline
Pentoxifylline Information

About Pentoxifylline

Pentoxifylline is a vasodilator, used in the treatment of peripheral vascular disease like intermittant claudication, Raynaud's syndrome. It may be useful in lowering blood sugar level, also reduces blood presure. Caution may be needed if given with antihypertensive or insulin as it may increase their effects

Indications

Pentoxifylline is primarily indicated in conditions like Cerebrovascular disease, Circulatory system disease, Raynaud"s phenomenon, and can also be given in adjunctive therapy as an alternative drug of choice in Peripheral vascular disease, Venous leg ulcers.

Contraindication

Pentoxifylline

Side Effects

The signs and symptoms that are produced after the acute overdosage of Pentoxifylline include Bradycardia, AV block.The symptomatic adverse reactions produced by Pentoxifylline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Urticaria, Pruritus, GI distention.

Warnings

Give pentoxifylline with caution to patients with chronic occlusive arterial disease of limb because it can cause other arteriosclerotic disease. Monitor the systemic blood pressure (B.P) especially in patients receiving antihypertensive drugs.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.