Oxymetazoline (HCl)
Oxymetazoline (HCl) Information

About Oxymetazoline (HCl)

Oxymetazoline (HCl) is a sympathomimetic amine of the imidazoline class.Oxymetazoline (HCl) is a direct agonist at alpha-adrenergic receptors with no action on beta-adrenergic receptors. Oxymetazoline (HCl) is used as a nasal decongestant in allergic rhinitis, and also as a ocular decongestant in allergic conjunctivitis (whether seasonal or perennial). Chemically Oxymetazoline (HCl) is 3-[(4,5-dihydro-1H-imidazol-2-yl) methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol hydrochloride. Oxymetazoline (HCl) is available for nasal and opthlamic administration.

Indications

Oxymetazoline (HCl) is primarily indicated in conditions like Ocular congestion, Otitis media, Rhinitis, Sinusitis, and can also be given in adjunctive therapy as an alternative drug of choice in Conjuctivitis.

Contraindication

Oxymetazoline (HCl) is contraindicated in conditions like Narrow-angle glaucoma.

Side Effects

The severe or irreversible adverse effects of Oxymetazoline (HCl), which give rise to further complications include Rhinitis medicamentosa.The signs and symptoms that are produced after the acute overdosage of Oxymetazoline (HCl) include Hypotension, Sedation.The symptomatic adverse reactions produced by Oxymetazoline (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Stinging on application, Dryness of eye.

Warnings

Use topical decongestant (oxymetazoline) only in acute conditions, not longer than 3 to 5 days. It should be use sparingly in all patients, especially in infants, children and in cardiac patients.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.