Nimesulide
Nimesulide Information
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Nimesulide
medicine,pricing, side effects of Nimesulide medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Nimesulide
Nimesulide is NSAID ( non steroidal antinflammatory drug) reported to be selective inhibitor of cyclo-oxygenase-2 (COX-2) it has been given by mouth or rectally for inflammatory condition, fever and pain.
Indications
Nimesulide is primarily indicated in conditions like Bursitis, Fever, fever, Gynecological infections, Inflammation, Osteoarthritis, Pain, Rheumatoid arthritis, Tendinitis, Thrombophlebitis, Trauma, and can also be given in adjunctive therapy as an alternative drug of choice in Ent infections.
Contraindication
Nimesulide is contraindicated in conditions like GI ulceration,GI hemorrhage.
Side Effects
The severe or irreversible adverse effects of Nimesulide, which give rise to further complications include Stevens johnson syndrome, lyells syndrome, hepatoxicity.Nimesulide produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Nimesulide therapy.The signs and symptoms that are produced after the acute overdosage of Nimesulide include Hypotension, Hypothermia.The symptomatic adverse reactions produced by Nimesulide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Nausea, Pain, VertigoX, Thrombocytopenia, Melena.
Warnings
Nimesulide must be used with care among patients with a history of bleeding, with illnesses of the upper gastrointestinal tract and to subjects undergoing treatment with anticoagulants or drugs that inhibit platelet aggregation. The patients must be under direct medical supervision while taking substances with limited gastric tolerance at the same time. Since the drug is eliminated mainly through the kidneys, patient with the renal insufficiency must have a lower dosage depending on the glomerular filtration rate. The product must not be administered to the patient with severe renal insufficiency. The product can cause water retention, therefore it must not be administered to the patient with reduced cardiac function. Patients whose activity require alertness must take the product with care in case they notice drowsiness or vertigo during therapy . Cases of visual disturbances when using other non-steroidal anti-inflammatory drugs have been reported, If eye problems appear, the treatment must be interrupted and an eye examination must be performed.
High Risk Groups
Drug should not be given to Pregnant Mothers, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Nimesulide Dosage for Adults
| Dose | 0 to 100 mg |
| Single Dose | 50 (50) |
| Frequency | 12 hourly |
| Route | PO |
| Note: Increase upto 200mg bid. | |
| Dose | 3 to 0 % |
| Single Dose | 1.5 (1.5) |
| Frequency | As recommended. |
| Route | topical |
| Note: Increase upto 200mg bid. |
Nimesulide Dosage for Neonatal
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| Single Dose | |
| Frequency | |
| Route | |
| Note: Not recommended in this age group |
Nimesulide Dosage for Paedriatic
| Dose | |
| Single Dose | |
| Frequency | |
| Route | |
| Note: Not recommended in this age group |
Brands
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