Naproxen
Naproxen Information
Find all the information of Naproxen medicine and drugs available in Pakistan. Read the pricing, side effects, usage, instructions and dosage of Naproxen by .
Naproxen
medicine,pricing, side effects of Naproxen medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug that also possesses antipyretic and analgesic properties. Chemically Naproxen is identified as (+)-6-methoxy-a-methyl-2-naphthalene acetic acid Naproxen is a propionic acid derivative related to ibuprofen, ketoprofen, etc. Many pharmacodynamic similarities exist among these agents, which are usually better tolerated than aspirin or indomethacin. It also has been shown superior to ergotamine in the treatment of migraine. It was approved by the FDA in 1976. The antiinflammatory effects of it may result from the peripheral inhibition of prostaglandin synthesis secondary to inhibition of the enzyme cyclooxygenase. Prostaglandins sensitize pain receptors, and their inhibition is believed to be responsible for the analgesic effects of it
Indications
Naproxen is primarily indicated in conditions like Acute gout, Acute spasm and spasm in diagnostic procedures, Differential diagnosis of acth-dependent cushing"s syndrome, Dysmenorrhoea, Fever, fever, Glaucoma, Headache, Migraine, Musculoskeletal disorders, Ocular hypertension, Pain, Rheumatoid arthritis, Surgical infections, Trauma.
Contraindication
Naproxen is contraindicated in conditions like Hypersensitivity reactions.
Side Effects
The severe or irreversible adverse effects of Naproxen, which give rise to further complications include Hepatitis, Aplastic anemia, Hemolytic anemia, Aplastic anemia, Hemolytic anemia, Anaphylactoid reactions, Granulocytopenia, Nephrotic syndrome, Peptic ulceration, Acute renal failure, Nephritis, Hemolytic anemia, Breast cancer, Pseudoporphyria, Aplastic anemia, GI perforation.Naproxen produces potentially life-threatening effects which include Gastric erosion and ulceration, Aplastic Anemia, Anaphylaxis, Gastric hemorrhage, Aplastic anemia. which are responsible for the discontinuation of Naproxen therapy.The signs and symptoms that are produced after the acute overdosage of Naproxen include Nausea, Vomiting, Seizures, Drowsiness, Anemia, GI disturbances, Hypertension, Indigestion, Hearing loss.The symptomatic adverse reactions produced by Naproxen are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Drowsiness, Nausea, Constipation, Tinnitus, Abdominal pain, Visual disorders, Stomatitis, Jaundice, Dyspepsia, Malaise, Depression, Heart burn, Light headedness, Increased intracranial pressure, Glaucoma, Flu like syndrome, Dreams abnormality, dizziness, dyspepsia, Cognitive dysfunctions, Pseudoporphyria, Leukocytoclastic vasculitis, Allergic Pneumonitis, Photodermatitis, Decreased Creatinine Clearance, Reversible Keratopathy.
Warnings
Naproxen should be used with caution in patients with intrinsic coagulation defects and those on anticoagulant therapy. Naproxen may lead to new hypertension or worsening of existing hypertension. Cautions should be taken in heart failure,ulcer or GI bleeding. It should be used with caution in patients with other condition predisposing to fluid retention. It should be used with extra care in the presence of existing controlled infection. Perform periodic auditory function test during chronic therapy. Discontinue drug if skin reaction occurs.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Naproxen Dosage for Adults
| Dose | 250 to 500 mg |
| Single Dose | 380 (375) |
| Frequency | 12 hourly |
| Route | PO |
| Note: For Musculoskeletal disorder and Dysmenorrhea .Initially given 500 mg which is followed by 250 mg every 6 or 8 hr | |
| Dose | 250 to 1000 mg |
| Single Dose | 620 (625) |
| Frequency | 12 hourly |
| Route | PO |
| Note: For rheumatic disease and chronic pain.It should be taken after food | |
| Dose | 750 mg |
| Single Dose | 750 (750) |
| Frequency | 12 hourly |
| Route | PO |
| Note: For Acute Gout .Initially given 500 mg which is followed by 250 mg every 8 hr | |
| Dose | 500 mg |
| Single Dose | 500 (500) |
| Frequency | As recommended. |
| Route | Rectal (supp) |
| Note: For Musculoskeletal Disorder and Dysmenorrhea .1 suppository given at Bed time followed by 1 suppository in the morning. |
Naproxen Dosage for Paedriatic
| Dose | 5 to 0 mg/kg |
| Single Dose | 2.5 (2.5) |
| Frequency | 12 hourly |
| Route | Oral |
| Note: 1 month to 18 years which may be increased to 10-15mg/kg twice daily. |
Brands
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