Naphazoline
Naphazoline Information

About Naphazoline

Naphazoline is a sympathomimetic agent with marked alpha-adrenergic activity. Chemically Naphazoline is 2-(1-naphthylmethyl)-2-imidazoline. Naphazoline is used topically on nasal mucosa where its vasoconstrictor effect leads to reduce secretion and mucosal swelling (e.g in allergic rhinitis). Prolonged use may lead to rebound nasal congestion and secretion. Naphazoline is also used in allergic and inflammtory condition of eyes.

Indications

Naphazoline is primarily indicated in conditions like Corneal vascularity, Hyperaemia, Itching, Nasal congestion, and can also be given in adjunctive therapy as an alternative drug of choice in Sinusitis.

Contraindication

Naphazoline is contraindicated in conditions like Asthma,Diabetes mellitus,Narrow-angle glaucoma.

Side Effects

The severe or irreversible adverse effects of Naphazoline, which give rise to further complications include Rebound congestion, Increased IOP (intraocular pressure).The symptomatic adverse reactions produced by Naphazoline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Nervousness, Dry mouth, Irritation, Sneezing, Blurring of vision, Mydriasis, Stinging on application, Dry mouth, nervousness, Nervousness, dizziness.

Warnings

Use topical decongestant only in acute conditions, not longer than 3 to 5 days. Naphazoline should be used sparingly in all patients, especially in infants, children and in cardiac patients.

High Risk Groups

Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.