Moxifloxacin
Moxifloxacin Information

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Moxifloxacin

medicine,pricing, side effects of Moxifloxacin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Moxifloxacin

Moxifloxacin is an antibiotic belongs to 3rd group of fluoroquinolones. Fluoroquinolones are potent bactericidal agents against E. coli and various species of Salmonella, Shigella, Enterobacter, Campylobacter and Neisseeria, it has excellent activity against S. pneumoniae. Moxifloxacin is used in respiratory tract infections, in urinary tract infectionsand in bone and soft tissue infections.

Indications

Moxifloxacin is primarily indicated in conditions like Acute bacterial sinusitis, Chronic bronchitis, Lower respiratory tract infections, Oedema, Pneumonia, Short-term treatment of severe congestive heart failure, Sinusitis, Skin infections, Soft tissue infections, Upper respiratory tract infections, and can also be given in adjunctive therapy as an alternative drug of choice in Bacterial conjunctivitis.

Contraindication

Moxifloxacin is contraindicated in conditions like Heart failure,Bradycardia,Liver diseases,Electrolyte disturbance.

Side Effects

The severe or irreversible adverse effects of Moxifloxacin, which give rise to further complications include Hypotension, Hypotension, Hyperglycemia, Dyspnea, Hyperuricemia, Hyperglycemia, Hyperlipidemia.Moxifloxacin produces potentially life-threatening effects which include Anaphylactic reactions, Atrial fibrillation. which are responsible for the discontinuation of Moxifloxacin therapy.The symptomatic adverse reactions produced by Moxifloxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Nausea, Vomiting, Diarrhea, Myalgia, Restlessness, Tachycardia, Tremors, Insomnia, Abdominal pain, Sweating, Skin rash, Dyspepsia, Pseudomembranous colitis, Hemolytic anemia, Thrombocytopenia, Edema, Hot flushes, Syncope, Gynecomastia, Abnormal LFT, Hypersensitivity reactions, Taste perversion, Superinfection, QT prolongation, Visual disturbances, dizziness, dyspepsia, Abnormal LFT, agranulocytosis, arthropathy, Tachycardia.

Warnings

It should be used with caution in patients with known or suspected central nervous system disorders which may predispose to seizures or lower the seizure threshold. As no pharmacokinetics or pharmacodynamic data are available in severe hepatic impairment, the use of moxifloxacin in this patients group is not recommended. Moxifloxacin should be used with caution in patients with known QT interval prolongation or uncorrected hypokalemia; in those receiving class IA (e.g quinidine or procaine amide) or class III antiarrhythmic agents (sotalol, ibutilide, amiodarone); and in patients who are receiving other agents known to increase the QT interval (e.g erythromycin, tricyclic antidepressants).

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Moxifloxacin Dosage for Adults

Dose 400 mg
Single Dose 400 (400)
Frequency 24 hourly
Route IV
Note: Given over 60 minutes.
Dose 400 mg
Single Dose 400 (400)
Frequency 24 hourly
Route PO
Note: For 5-10 days in exacerbation of chronic bronchitis.

Brands


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