Mesalazine
Mesalazine Information

About Mesalazine

Mesalazine is ingredient of sulphasalizine and Mesalazine is used in the treatment of ulcerative collitis. It can be given both by mouth as an enema.

Indications

Mesalazine is primarily indicated in conditions like Crohn's disease, Ulcerative colitis.

Contraindication

Mesalazine is contraindicated in conditions like Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Mesalazine, which give rise to further complications include Hepatitis, Bronchospasm, Bronchospasm, Nephrotic syndrome, Blood dyscrasias, blood dyscrasias.Mesalazine produces potentially life-threatening effects which include Myocarditis, Pericarditis. which are responsible for the discontinuation of Mesalazine therapy.The symptomatic adverse reactions produced by Mesalazine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Alopecia, Diarrhea, Fever, Rashes, Hair loss, Chest pain, Leukopenia, Paresthesias, Abdominal discomfort, Alopecia.

Warnings

Avoid mesalazine in patients with impaired renal function or salicylate or sulfite hypersensitivity. It should be used with caution in elderly. Avoid use in children under 2 years of age. If blood dyscrasia is suspected treatment should be stopped immediately and blood count should performed.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.