Meprobamate
Meprobamate Information

About Meprobamate

Meprobamate is a propyl alcohol derivative (propanediol carbamate), having sedative, muscle rexalant and anticonvulsant actions. Meprobamate is effective to relieve anxiety, nervousness, headache and tension.

Indications

Meprobamate is primarily indicated in conditions like Anxiety, Insomnia, Musculoskeletal disorders.

Contraindication

Meprobamate is contraindicated in conditions like Alcohol dependence,Porphyrias,Respiratory depression,Acute pulmonary insufficiency,Breast feeding.

Side Effects

The severe or irreversible adverse effects of Meprobamate, which give rise to further complications include Convulsions, Nausea, Vomiting, Tachycardia, Fever, Thrombocytopenia, Hypotension, Angioneurotic edema, Bronchospasm, Hypotension, Bronchospasm, Agranulocytosis, Thrombocytopenic purpura, Chills, parasthesia, Tachycardia.Meprobamate produces potentially life-threatening effects which include Porpyhria. which are responsible for the discontinuation of Meprobamate therapy.The signs and symptoms that are produced after the acute overdosage of Meprobamate include Coma, Shock, Vasomotor collapse, Respiratory collapse.The symptomatic adverse reactions produced by Meprobamate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Ataxia, Nausea, Diarrhea, Skin rashes, Sedation, Skin rashes, dizziness, Ataxia.

Warnings

Meprobamate should be used with caution in patients with respiratory disease; muscle weakness; epilepsy,depression (may include seizures); history of drug or alcohol abuse; marked personality disorder; pregnancy; elderly and debilitated; hepatic and renal impairment; avoid prolonged use abrupt withdrawl may precipitate convulsions. DRIVING: Drowsiness may affect performance of skilled tasks (e.g driving); effects of alcohol enhanced.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.