Magnesium Sulphate
Magnesium Sulphate Information

About Magnesium Sulphate

Magnesium Sulphate is a saline laxative. Magnesium Sulphate is used in constipation. It increases the bulk of intestinal contents and cause defecation. Magnesium Sulphate is also used to control seizures in pregnancy, to treat low magnesium levels, problems related to kidney conditions (nephritis) in children, to prevent premature contractions in pregnancy, to treat heart attack and asthma patients.

Indications

Magnesium Sulphate is primarily indicated in conditions like Constipation, Convulsions, Eclampsia, Emergency treatment of serious arrhythmias, Hyperacidity, Hypomagnesaemia, Nephritis, Prevention of seizure recurrence in pre-eclampsia, Seizures, Suspected myocardial infarction, Symptomatic hypomagnesaemia, To prevent recurrence of defecits, and can also be given in adjunctive therapy as an alternative drug of choice in Premature labour.

Contraindication

Magnesium Sulphate is contraindicated in conditions like Myocardial infarction,Heart block,Toxaemia of pregnancy,Renal impairment.

Side Effects

The severe or irreversible adverse effects of Magnesium Sulphate, which give rise to further complications include Diarrhoea, Bradycardia, CNS depression, Hypocalcemia, Hypermanganesemia.Magnesium Sulphate produces potentially life-threatening effects which include Coma, Cardiac Arrest, Cardiac arrest, Respiratory paralysis. which are responsible for the discontinuation of Magnesium Sulphate therapy.The symptomatic adverse reactions produced by Magnesium Sulphate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Drowsiness, Confusion, Hypotension, Flushing, Muscle weakness, Nausea and vomiting, Slurred speech, Respiratory depression, Confusion.

Warnings

Do not exceed prescribed dose because it will cause diarrhea.Maintain urine output at level of 100ml every 4hrs.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.