Loteprednol
Loteprednol Information

About Loteprednol

loteprednol (as Loteprednol Etabonate) contains a sterile, topical anti-inflammatory corticosteroid for ophthalmic use. Loteprednol etabonate is a white to off white powder.chemically it is chloromethyl 17a-[(ethoxycarbonyl)oxy]-11ß-hydroxy-3-oxoandrosta-1,4-diene-17ß-carboxylate. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye.

Indications

loteprednol is primarily indicated in conditions like Acne rosacea, Conjunctivitis, Herpes zoster, Iritis, Keratitis, Uveitis.

Contraindication

loteprednol

Side Effects

The symptomatic adverse reactions produced by loteprednol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Eye Pain, Foreign body sensation, elevated intraocular presure, posterior subcapsular cataract formation, herpes simplex, anterior chamber inflammation.

Warnings

Intraocular pressure (IOP) increase - Prolonged use of corticosteroids may result in glaucoma with damage to theoptic nerve, defects in visual acuity and fields of vision. If thisproduct is used for 10 days or longer, IOP should be monitored.Cataracts , delay healing after cataract surgery,bacterial infection, viral infection, funcl infection,patients should not wear contact lenes during their course of therapy with loteprednol.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.