Lindane
Lindane Information

About Lindane

Lindane is a gamma isomer of hexachlorocyclohexane. It was commonly called gamma benzene hexachloride which was a misnomer because benzene ring is not present in this compound. Lindane is a powerful parasiticide with a rapid action against the majority of external parasites, including Pediculus humanus var. capitis. Lindane is used topically on skin or hair for lice and scabies. Lindane is only available for topical administeration.

Indications

Lindane is primarily indicated in conditions like Pediculosis, Scabies.

Contraindication

Lindane is contraindicated in conditions like Hypersensitivity,Seizures,Skin inflammation.

Side Effects

The severe or irreversible adverse effects of Lindane, which give rise to further complications include Insomnia, Paresthesia, Giddiness.Lindane produces potentially life-threatening effects which include Seizures, Aplastic Anemia, Aplastic anemia. which are responsible for the discontinuation of Lindane therapy.The signs and symptoms that are produced after the acute overdosage of Lindane include Vomiting, Convulsions, Collapse, Restlessness, Muscular spasm, Loss of equilibrium.The symptomatic adverse reactions produced by Lindane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Restlessness, Abdominal cramps, Confusion, Cough, Skin irritation, Contact dermatitis, Psoriasis, Confusion, dizziness, Contact dermatitis.

Warnings

Lindane should not be used in patients with seizure disorders, have open wounds or sores or are allergic to lindane. Elderly persons may be more sensitive to the effects of this medication and a dose reduction may be required. Pregnant women should not be treated more than twice during the pregnancy. Lidane should not be used in neonates, infants 2 years old and younger because of the possibility of high systemic absorption. Children 10 years old and younger also should be treated cautiously with lindane because of an increased potential for toxicity.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.