Letrozole
Letrozole Information

About Letrozole

Letrozole is a new oral nonsteroidal inhibitor of aromatase activity. Letrozole is used to treat advanced breast cancer in women in whom tamoxifen is failed.

Indications

Letrozole is primarily indicated in conditions like Breast cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Advanced breast cancer in postmenopausal women.

Contraindication

Letrozole

Side Effects

The severe or irreversible adverse effects of Letrozole, which give rise to further complications include Thromboembolic disorder.The symptomatic adverse reactions produced by Letrozole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Myalgia, Dyspnea, Abdominal pain, Rashes, Coughing, Nausea and vomiting, Hot flushes, SomnolenceX, Vaginal dryness, Stevens Johnson syndrome, dizziness, Bone fracture.

Warnings

Letrozole should be used with caution in patients with any allergies (especially drug allergies) or liver disease. Limit alcohol intake as it may increase the side effects of this drug. It should be used with caution while performing tasks requiring mental alertness (e.g.driving), because this drug may cause drowsiness. It is not recommended for use during pregnancy.

High Risk Groups

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.