Lansoprazole
Lansoprazole Information
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Lansoprazole
medicine,pricing, side effects of Lansoprazole medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Lansoprazole
Lansoprazole is an acid proton pump inhibitor. Lansoprazole is a benzimidazole sulfoxide derivarive and produces long lasting inhibition of gastric acid secretion. Lansoprazole is a chiral cmpound with one chiral center, synthsized as a racemic mixture and both enantiomers are active. Chemically Lansoprazole is identified as 2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridinyl] methyl] sulfinyl ]-1H-benzimidazole. Lansoprazole is effective in the treatment of duodenal or gastric ulcer, gastroesophageal reflux disease and in the treatment of zollinger-ellison syndrome. Lansoprazole is administered orally.
Indications
Lansoprazole is primarily indicated in conditions like Acid-related dyspepsia, Benign gastric ulcer, Duodenal ulcer, Duodenal ulcer associated with h. Pylori, Esophagitis, Gastric ulcer, Gastro-oesophageal reflux disease, Heart burn, Helico-bacter pylori positive duodenal ulcer, NSAID-associated gastric and duodenal ulcers, NSAID-associated gastric and duodenal ulcers (prophylaxis), NSAID-associated gastric or duodenal ulcers, Peptic ulcer, Resistant ulcers, Zollinger-ellison syndrome, and can also be given in adjunctive therapy as an alternative drug of choice in GI bleeding.
Contraindication
Lansoprazole is contraindicated in conditions like Liver diseases.
Side Effects
The severe or irreversible adverse effects of Lansoprazole, which give rise to further complications include Epidermal necrolysis, Atrophic gastritis.The symptomatic adverse reactions produced by Lansoprazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Diarrhea, Constipation, Rashes, Pruritus.
Warnings
Lansoprazole should be used with caution in patients with any pre-existing liver disease or in case of any allergy. It should be used only if clearly needed during pregnancy or lactation. Since gastric acid secretion and other phsiological functions are decreased in elderly patients lansoprazole should be administered with caution.
High Risk Groups
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Lansoprazole Dosage for Adults
| Dose | 15 to 30 mg |
| Single Dose | 22 (22.5) |
| Frequency | 24 hourly |
| Route | PO |
| Note: Frequency may increased to twice.15 mg/day is given on an empty stomach. |
Lansoprazole Dosage for Neonatal
| Dose | |
| Single Dose | |
| Frequency | |
| Route | |
| Note: Not recommended in this age group |
Lansoprazole Dosage for Paedriatic
| Dose | 15 mg |
| Single Dose | 15 (15) |
| Frequency | 24 hourly |
| Route | 30 mg or less. |
| Dose | 30 mg |
| Single Dose | 30 (30) |
| Frequency | 24 hourly |
| Route | More than 30 kg |
Brands
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