Isotretinoin
Isotretinoin Information

Find all the information of Isotretinoin medicine and drugs available in Pakistan. Read the pricing, side effects, usage, instructions and dosage of Isotretinoin by .


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Isotretinoin

medicine,pricing, side effects of Isotretinoin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Isotretinoin

Isotretinoin is the 13-cis-retinoic acid, a vitamin A derivative, used systematically for treatment of severecystic and conglobulate acne acne not responsive to antibiotic therapy. Thought to act directly on sebaceous glands in the skin to reduce sebum production and alters the lipid composition of the skin surface.

Indications

Isotretinoin is primarily indicated in conditions like Gram negative folliculitis, Keratiniztion disorders, Mild acne in patients with dysmorphohobia, Rosacea, Severe acne.

Contraindication

Isotretinoin is contraindicated in conditions like Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Isotretinoin, which give rise to further complications include Thrombocytopenia, Hepatitis, Myalgia, Hypercholesterolemia, Hypercholesterolemia.Isotretinoin produces potentially life-threatening effects which include Depression. which are responsible for the discontinuation of Isotretinoin therapy.The symptomatic adverse reactions produced by Isotretinoin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Alopecia, Abdominal pain, Blurred vision, Arthralgia, Erythematous rash, Cheilitis, Conjunctivitis, Nasal bleeding, Photophobia, Skin sepsis, Desquamation, Facial dermatitis, Epistaxis, Paronychia, Blepharoconjunctivitis, Alopecia, Erythematous rash, Pruritis, Skin fragility, Hearing impairment, Impaired night vision.

Warnings

Isotretinoin should be used with caution in patients with medical history, including diabetes, family history of high blood fats (triglycerides), depression or any allergy (including drugs e.g. Tetracyclines). Do not donate blood while taking isotretinoin and for at least one month after stop taking it. Avoid exposure to the sun and sunlamps use a sunscreen and wear protective clothing when exposed to direct sunlight. Isotretinoin can affect night vision. Be cautious when driving or operating any machinery after dark. Avoid the use of alcohol while taking this. It should not be used during pregnancy or lactation. Do not apply isotretinoin gel to your lips, mouth and mucous membrane or in the angle of your nose.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Isotretinoin Dosage for Adults

Dose 35 to 70 mg
Single Dose 52 (52.5)
Frequency 24 hourly
Route PO
Dose 0.05 %
Single Dose 0.05 (0.05)
Frequency 12 hourly
Route Topical
Note: For 8 Weeks

Isotretinoin Dosage for Neonatal

Dose
Single Dose
Frequency
Route
Note: Not recommended in this age group

Isotretinoin Dosage for Paedriatic

Dose Doses not established for this age group
Single Dose
Frequency
Route

Brands


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