Iopamidol
Iopamidol Information

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Iopamidol

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About Iopamidol

Iopamidol is an iodinated nonionic diagnostic agent, used for a variety of radiographic procedures including angiography, arhtrography, myelography, and urography. Iopamidol has also been used orally or by enema for visualization of the gastro-intestinal tract.

Indications

Iopamidol is primarily indicated in conditions like Angiography, Arthrography, Myelography, and can also be given in adjunctive therapy as an alternative drug of choice in Urography.

Contraindication

Iopamidol is contraindicated in conditions like Allergy,Renal impairment,Hypersensitivity to any component of product.

Side Effects

The severe or irreversible adverse effects of Iopamidol, which give rise to further complications include Severe Renal impairement.Iopamidol produces potentially life-threatening effects which include Anaphylactoid reactions, Transient ECG abnormalities, Bronchospasm, Dyspnea, Acute Renal Failure, Bronchospasm, Acute renal failure, Severe urticaria. which are responsible for the discontinuation of Iopamidol therapy.The symptomatic adverse reactions produced by Iopamidol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Nausea, Vomiting, Tachycardia, Sweating, Pruritus, Bradycardia, Hypotension, Coughing, Flushing, Sneezing, Rhinitis, Metallic taste, Sensation of warmth, Pallor, Visual disturbances, dizziness.

Warnings

Iopamidol should be administered with great caution to patients with asthma or a history of allergy and should be avoided in patients with known hypersensitivity to contrast media or to iodine. Caution is needed in patients with hepatic or renal impairment or others who may be at increased risk of renal failure.

High Risk Groups

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Iopamidol Dosage for Adults

Dose 10 ml
Single Dose 10 (10)
Frequency As recommended.
Route IT
Note: Cervical myelography by lateral cervical injection: 10 mL of a solution containing the equivalent of 200 mg of iodine per mL.
Dose 10 to 15 ml
Single Dose 12 (12.5)
Frequency As recommended.
Route IT
Note: Lumbar and Thoracic myelography by lumbar injection: 10 to 15 mL of a solution containing the equivalent of 200 mg of iodine per m
Dose 50 to 100 ml
Single Dose 75 (75)
Frequency As recommended.
Route IV
Note: Urography, excretory: Intravenous, 50 to 100 mL of a solution containing the equivalent of 250 mg of iodine per mL; or 50 mL of a solution containing the equivalent of 300 mg of iodine per mL, by rapid administration.
Dose 130 ml
Single Dose 130 (130)
Frequency As recommended.
Route IV
Note: CT of the body: Intravenous, 130 mL of a solution containing the equivalent of 250 mg of iodine per mL; or 50 to 100 mL of a solution containing the equivalent of 300 mg of iodine per mL; or 81 mL of a solution containing the equivalent of 370 mg of iodine per mL, by rapid administration.

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