Iohexol
Iohexol Information

About Iohexol

Iohexol is a non-ionic, water soluble, low osmolality, iodinated, organic radiological contrast medium of exceptionally low clinical toxicity. Iohexol is used in cardiac angiography, myelography, urogrphy, arthrography, and ventriculography etc. Iohexol is prepared by chemical synthesis. Iohexol is administered intrathecaly, and intravascularly.

Indications

Iohexol is primarily indicated in conditions like Angiography, Metastatic lung cancer, Metastatic pancreatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Arthrography, Computed tomography scans, Myelography, Urography.

Contraindication

Iohexol is contraindicated in conditions like Cough,Dyspepsia,Fever,fever,Pulmonary disease.

Side Effects

The severe or irreversible adverse effects of Iohexol, which give rise to further complications include Hypotension, Bronchospasm, Hypotension, Bronchospasm, Oedema.Iohexol produces potentially life-threatening effects which include Anaphylactic shock, Cardiac arrhythmias, Bronchospasm, Bronchospasm, Angioneurotic edema, Cardiovascular collapse, Acute pulmonary edema, Angioneurotic edema. which are responsible for the discontinuation of Iohexol therapy.The symptomatic adverse reactions produced by Iohexol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Maculopapular rash, Confusion, Urticaria, Pruritus, Erythema, Flushing, Sneezing, Visual & sleep disturbances, Rhinitis, Faintness, Metallic taste, Convulsions, Backache, Perineal sensation, Salivary gland swelling, Neck stiffiness, Vein irritation at injection site, Aseptic maningitis, Confusion, dizziness, faintness.

Warnings

Iohexol should be administered with great caution in patients with asthma and history of allergy, and should be avoided to patients with known hypersensitivity to iodine or contrast media. Caution is needed in patients with severe hepatic (liver) or renal impairment or who may be at a risk of renal failure. Dehydration patients should have their fluid and electrolyte balance corrected before administration of contrast medium. It should be used with extreme caution in patients with hypertension, cardiac disease, phaeochromocytoma, sickle-cell anemia or hypothyroidism. Avoid use during pregnancy.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.