Interferon Beta
Interferon Beta Information

About Interferon Beta

Interferons are potent cytokines that possess antiviral, immunomodulating and antiproliferative actions. The interferones bind to specific cell-surface receptors that initiate a series of intracellular events, induction of certain enzymes, inhibition of cell-proliferation, and enhancement of immune activities. It (IFNB) is a type of interferon produced by fibroblasts and epithelial cells. The term "it" used here encompasses products that are further differentiated as either it-1a or it-1b. it-I a, a 166-amino acid recombinant glycoprotein, and it-I b, a 165-amino acid recombinant protein, used in the treatment of multiple sclerosisto reduce the frequency of clinical exacerbations.

Indications

Interferon Beta is primarily indicated in conditions like Condyloma acuminata, Hairy cell leukaemia, Hepatitis B, Hepatitis C, Herpes simplex infections, Multiple sclerosis.

Contraindication

Interferon Beta is contraindicated in conditions like Depression,Lactation.

Side Effects

The severe or irreversible adverse effects of Interferon Beta, which give rise to further complications include Sinus tachycardia, Neutropenia, Hypothyroidism, Depression, Pancytopenia, Hyperthyroidism.The symptomatic adverse reactions produced by Interferon Beta are more or less tolerable and if they become severe, they can be treated symptomatically, these include Alopecia, Anorexia, Fever, Skin reactions, Confusion, Malaise, Arthralgia, Swelling, Anemia, Muscle aching, Leukopenia, Skin redness, Lymphopenia, Confusion, Alopecia.

Warnings

It should be used with caution in patients with any pre-existing liver, kidney, heart or thyroid disease, blood disorders, history of depression or other mental condition, lung disease, diabetes, seizures, brain tumor, multiple sclerosis, lupus, sarcoidosis or any drug allergy. It should be used with caution when engaging in activities requiring alertness. Limit alcohol intake. It should be used only when clearly needed during pregnancy.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.