Insulin
Insulin Information

About Insulin

Insulin is a hormone which is proteinic in nature. It is secreted by a group of cells called islet cells within the pancreas. Insulin is used medically to treat some forms of diabetes mellitus. Insulin from animal source differs some what in regulatory function strength in humans because of variations.Procine insulin is especially close to the human version. Macleod and Banting were awarded the NOBLE PRIZE in physiology in 1923 for discovery of insulin.

Indications

Insulin is primarily indicated in conditions like Diabetes insipidus, Diabetes mellitus, and can also be given in adjunctive therapy as an alternative drug of choice in Adjunct in GI-disorders, Myocardial infarction, Stroke.

Contraindication

Insulin is contraindicated in conditions like Hypoglycaemia,Hypersensitivity to any component of product.

Side Effects

The severe or irreversible adverse effects of Insulin, which give rise to further complications include Allergy, Hypokalemia, Hyperglycemia, Blurred vision, Hypoglycemia.Insulin produces potentially life-threatening effects which include Convulsions. which are responsible for the discontinuation of Insulin therapy.The signs and symptoms that are produced after the acute overdosage of Insulin include Hypotension, Fainting, Headache, Weakness, Dyspnea.The symptomatic adverse reactions produced by Insulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Rashes, Redness, Swelling.

Warnings

Glucose monitoring should be done.Patient should be careful in timing of insulin dosing,meal planing,regular exercise and monitoring of blood glucose.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.