Insulin Lispro
Insulin Lispro Information

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Insulin Lispro

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About Insulin Lispro

Insulin Lispro is a recombinant human insulin analogue. Insulin Lispro is used in the treatment of diabetes mellitus. It has a faster onset and shorter duration of action than soluble insulin.

Indications

Insulin Lispro is primarily indicated in conditions like Iddm, Type II diabetes mellitus.

Contraindication

Insulin Lispro is contraindicated in conditions like Hypoglycaemia,Hypersensitivity to any component of product.

Side Effects

The severe or irreversible adverse effects of Insulin Lispro, which give rise to further complications include Wheezing, Hypoglycemia, Hives, Lipoatrophy, Muscle Cramps, Difficulty in breathing.The symptomatic adverse reactions produced by Insulin Lispro are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Constipation, Peripheral edema, Pharyngitis, Allergic reactions, Redness, Cough, Rhinitis, Swelling at injection site, Infection, Swelling of feet.

Warnings

Hypoglycemia is the most common adverse effect associated with insulins, including insulin lispro. As with all insulins, the timing of hypoglycemia may differ among various insulin formulations. Glucose monitoring is recommended for all patients with diabetes. Any change of insulin should be made cautiously and only under medical supervision. The requirements for insulin may be reduced in patients with renal impairment. Although impaired hepatic function does not affect the absorption or disposition of insulin lispro, careful glucose monitoring and dose adjustments of insulin, including Humalog, may be necessary.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Insulin Lispro Dosage for Adults

Dose 0.5 to 1.2 units/kg/day
Single Dose 0.85 (0.85)
Frequency As recommended.
Route SC
Note: The dosage of insulin lispro must be individualized. Blood glucose monitoring is essential in all patients receiving insulin therapy. It may be administered by continuous subcutaneous infusion by an external insulin pump. Do not use diluted or mixed insulins in external insulin pumps. Infusion sites should be rotated within the same region to reduce the risk of lipodystrophy . Change insulin lispro in the reservoir at least every 7 days, change the infusion sets and the infusion set insertion site at least every 3 days.

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