Insulin Detemir
Insulin Detemir Information

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Insulin Detemir

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About Insulin Detemir

Insulin detemir is a long-acting human insulin analogue for maintaining the basal level of insulin. Insulin detemir differs from human insulin in that the amino acid threonine in position B30 has been omitted, and a C14 fatty acid chain has been attached to the amino acid B29.

Indications

Insulin Detemir is primarily indicated in conditions like Type I diabetes mellitus, Type II diabetes mellitus.

Contraindication

Insulin Detemir is contraindicated in conditions like Hypoglycaemia,Hypersensitivity to the drug.

Side Effects

The severe or irreversible adverse effects of Insulin Detemir, which give rise to further complications include Rashes, Wheezing, Sweating, Blurred vision.Insulin Detemir produces potentially life-threatening effects which include Shortness of breath. which are responsible for the discontinuation of Insulin Detemir therapy.The signs and symptoms that are produced after the acute overdosage of Insulin Detemir include Coma, Seizures, Hypoglycemia.The symptomatic adverse reactions produced by Insulin Detemir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic reactions, Weight gain, Hypersensitivity, lipodystropy.

Warnings

Glucose should be regularly monitored in all patients with diabetes. Glucose detimer is not to be used in insulin infusion pumps. Tell your doctor if you have or have ever had nerve damage caused by your diabetes, liver or kidney disease. If you are having surgery, including dental surgery, tell the doctor or dentist that you are using insulin detemir.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Insulin Detemir Dosage for Adults

Dose For patients treated with glucose detimer once-daily, the dose should be administered with the evening meal or at bedtime. For patients who require twice-daily dosing for effective blood glucose control, the evening dose can be administered either with the evening meal, at bedtime, or 12 hours after the morning dose.
Single Dose
Frequency
Route
Dose 0.1 to 0.2 U/kg
Single Dose 0.15 (0.15)
Frequency As recommended.
Route SC
Note: This dose is for insulin-naive patients with type 2 diabetes who are inadequately controlled on oral antidiabetic drugs.

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