Hydroxyethyl Starch
Hydroxyethyl Starch Information

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Hydroxyethyl Starch

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About Hydroxyethyl Starch

Hydroxyethyl Starch is a starch that is composed of more than 90 % of amylopectin. Hydroxyethyl Starch is a plasma voluma expander. Hydroxyethyl Starch is used in the managemnt of hypovolumic shock.

Indications

Hydroxyethyl Starch is primarily indicated in conditions like Burns, Hypovolaemia, Infections, Low blood volume, Shock, Trauma.

Contraindication

Hydroxyethyl Starch is contraindicated in conditions like Renal failure,Haemorrhage,Anuria,Oliguria,Coagulation disorder.

Side Effects

The severe or irreversible adverse effects of Hydroxyethyl Starch, which give rise to further complications include Increased serum amylase.Hydroxyethyl Starch produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Hydroxyethyl Starch therapy.The symptomatic adverse reactions produced by Hydroxyethyl Starch are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Tachycardia, Itching, Fall in BP.

Warnings

Caution should be observed before administering Hydroxyethyl Starch to patients with severe liver disease or severe bleeding disorders. In cases of severe dehydration, a crystalloid solution should be given first. Generally, sufficient fluid should be administered in order to avoid dehydration.

High Risk Groups

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Hydroxyethyl Starch Dosage for Adults

Dose 33 to 66 ml/ kg
Single Dose 50 (49.5)
Frequency As recommended.
Route IV Inf
Note: As Required
Dose 50 to 1000 ml
Single Dose 520 (525)
Frequency As recommended.
Route IV-inf
Note: As required.

Hydroxyethyl Starch Dosage for Paedriatic

Dose Safety and efficacy have not been established.
Single Dose
Frequency
Route

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