Human Albumin
Human Albumin Information

About Human Albumin

Human Albumin is a sterile, nonpyrogenic preparation of serum albumin obtained by fractionating blood, plasma, serum or placentas from healthy human donors. It maintains the blood volume. Human Albumin is used as plasma volume expander in the treatment of shock, burns and low level of blood protein to correct or prevent deficiency of blood volume. Human Albumin is aministered intravenously. It solutions were developed by the Cohn and his associates during the Second World War, specifically to provide an improved material for emergency transfusion to military casualties. A method was developed to produce relatively pure albumin solutions from large quantities of human plasma and this stil remains the basis of virtually all production of clinical albumin products.

Indications

Human Albumin is primarily indicated in conditions like Burns, HIV infection, Hypoalbuminaemia, Hypovolaemia, Shock, and can also be given in adjunctive therapy as an alternative drug of choice in Adult respiratory distress syndrome (ards).

Contraindication

Human Albumin is contraindicated in conditions like Congestive heart failure.

Side Effects

The severe or irreversible adverse effects of Human Albumin, which give rise to further complications include Oedema.Human Albumin produces potentially life-threatening effects which include Severe Hypotension, Severe hypotension, Transmission of infectious agent. which are responsible for the discontinuation of Human Albumin therapy.The signs and symptoms that are produced after the acute overdosage of Human Albumin include Hypotension, Volume overload.The symptomatic adverse reactions produced by Human Albumin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Chills, Urticaria, Nausea and vomiting.

Warnings

Albumin should be used only if clearly needed during pregnancy. It should be used with caution in patients with any pre-existing heart disease, kidney disease, liver disease, blood disorders, anemia or any allergy especially to protein

High Risk Groups

Drug should not be given to Cardiac / Hypertensive Patients, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.