Griseofulvin
Griseofulvin Information

About Griseofulvin

Griseofulvin is antifungal agent produced by Pencillium griseofulvum. It acts as a fungistatic. It has been largely replaced by a newer antifungal medications such as itraconazole and terbinafine.

Indications

Griseofulvin is primarily indicated in conditions like Dermatophytic infections, Fungal infection, Parkinson's disease.

Contraindication

Griseofulvin is contraindicated in conditions like Systemic lupus erythematosus,Porphyrias,Hepatic failure.

Side Effects

Griseofulvin produces potentially life-threatening effects which include Angioedema. which are responsible for the discontinuation of Griseofulvin therapy.The symptomatic adverse reactions produced by Griseofulvin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Diarrhea, Urticaria, Severe headache, Drug eruptions, Cholestasis, Leprosy.

Warnings

Avoid alcoholic beverages while taking Griseofulvin unless doctor gives permission, drinking alcohol during treatment with this drug could result in a rapid heart rate and flushing of the skin. It should be used cautiously during pregnancy only if clearly needed. Griseofulvin may increase sensitivity to sunlight, so wear protective clothing and an appropriate sunscreen or avoid sun lamps.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.