Goserelin (Acetate)
Goserelin (Acetate) Information

About Goserelin (Acetate)

Goserelin (Acetate) is anticancer agent, also called as antineoplastic drug. Goserelin (Acetate) is a synthetic peptide analoge of naturally occuring gonadotrophin releasing hormone. Goserelin (Acetate) is more potent than the natural hormone, has longer duration of action, and function as gonadotrophin releasing hormone agonist.

Indications

Goserelin (Acetate) is primarily indicated in conditions like Advanced breast cancer( er+ve early breast cancer), Before surgery in women who have anaemia due to uterine fibroids, Breast cancer and prostate cancer, Endometrial thinning before intra-uterine surgery, Endometriosis, Pituitary desensitisation, Prostate cancer, Prostatic cancer, Uterine fibroids.

Contraindication

Goserelin (Acetate)

Side Effects

The severe or irreversible adverse effects of Goserelin (Acetate), which give rise to further complications include Spinal cord compression, Ureteric obstruction.Goserelin (Acetate) produces potentially life-threatening effects which include Hypertestosteronemia, Elevated serum testosterone. which are responsible for the discontinuation of Goserelin (Acetate) therapy.The signs and symptoms that are produced after the acute overdosage of Goserelin (Acetate) include Elevated serum testosterone.The symptomatic adverse reactions produced by Goserelin (Acetate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Urticaria, Bone pain, Hot flushes, Anaphylaxis, Pruritis, Withdrwal bleeding.

Warnings

Goserelin should be used with caution in patients with history especially of any undiagnosed vaginal bleeding, urination problems, spinal cord problems and of any drug allergies. It is not recommended for use during pregnancy or lactation.polycystic overy disease, diabetes, ureteric obstruction. pinal cordcompression in men.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.