Fluprednisolone
Fluprednisolone Information

About Fluprednisolone

Fluprednisolone is a synthetic glucocorticoid (Corticosteroid class of steroid hormones formed in the adrenal gland). Fluprednisolone is used in the management of variety of conditions requiring systemic glucocorticoid therapy. Administered orally.

Indications

Fluprednisolone is primarily indicated in conditions like Inflammation.

Contraindication

Fluprednisolone is contraindicated in conditions like Hypersensitivity to the drug.

Side Effects

The symptomatic adverse reactions produced by Fluprednisolone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Urticaria, pruritis(less commonly), Haemoptysis, Mucosal haemorrhage.

Warnings

Fluprednisolone should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid causes growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred.

High Risk Groups

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.