Fluorometholone
Fluorometholone Information

About Fluorometholone

Fluorometholone is a corticosteroid. Chemically Fluorometholone is 9-Fluoro-11ß,17-dihydroxy-6a-methylpregna-1, 4-diene-3, 20-dione. Fluorometholone is used in the local treatment of inflammmation when applied as eye drops.

Indications

Fluorometholone is primarily indicated in conditions like Allergic conjunctivitis, Giant papillary conjunctivitis, Keratitis, Post-operative ocular inflammation, Vernal keratoconjunctivitis.

Contraindication

Fluorometholone is contraindicated in conditions like Fungal infection,Viral infection,Herpes simplex keratitis,Herpes simplex infections.

Side Effects

The severe or irreversible adverse effects of Fluorometholone, which give rise to further complications include Glaucoma, Cataract, Optic neuritis and atrophy, Increased IOP (intraocular pressure).The symptomatic adverse reactions produced by Fluorometholone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Field defects, Visual acuity, Delayed wound healing, Secondary ocular infection.

Warnings

Fluorometholone should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid causes growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3 months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred.

High Risk Groups

Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.