Fluconazole
Fluconazole Information
Find all the information of Fluconazole medicine and drugs available in Pakistan. Read the pricing, side effects, usage, instructions and dosage of Fluconazole by .
Fluconazole
medicine,pricing, side effects of Fluconazole medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Fluconazole
Fluconazole is antifungal agent. Fluconazole is a substituted triazole derivetive. The requirement for intravenous administration and the toxicity of the older antifungal agents created a need for antifungal agents with a better therapeutic profile. The relatively non-toxic oral azole medications represent the first major advance in this direction. Since their introduction in the 1980s, these medications have played an increasingly important role in the systemic therapy of fungal disease.
Indications
Fluconazole is primarily indicated in conditions like Adjunctive therapy without valproate, Candidiasis, Cryptcoccal meningitis, Fungal infection, Neurogenic bladder, Oropharangeal candidiasis, Parkinsonism, Pityriasis versicolor, Vaginal infections, and can also be given in adjunctive therapy as an alternative drug of choice in Bone marrow transplantation, Cryptococcal infections including meningitis, Esophagitis, Urinary tract infection.
Contraindication
Avoid driving or hazardous activity until you know how fluconazole will affect you. Your reactions could be impaired.
Side Effects
The severe or irreversible adverse effects of Fluconazole, which give rise to further complications include Alopecia, Thrombocytopenia, Elevated alkaline phosphatase concentration, Eelvated hepatic enzymes, Hyperlipidemia, Elevated alkaline phosphatase concentration.Fluconazole produces potentially life-threatening effects which include Severe skin reactions in AIDS, Hepatic necrosis, Death. which are responsible for the discontinuation of Fluconazole therapy.The signs and symptoms that are produced after the acute overdosage of Fluconazole include Hallucinations, Paranoid psychosis.The symptomatic adverse reactions produced by Fluconazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Abdominal pain, Rashes, Hypokalemia, Pallor, Anaphylaxis, Leucopenia, dizziness.
Warnings
Fluconazol should be used with caution in patients with liver disease, kidney disease or of any drug allergy. This medication should be used only when clearly needed during pregnancy. Avoid fluconazole during lactation.childern not recommended under one year.Dose adjusted in renal impairment.
High Risk Groups
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Fluconazole Dosage for Adults
| Dose | 100 to 800 mg /day |
| Single Dose | 450 (450) |
| Frequency | 24 hourly |
| Route | IV |
| Note: for Mucocutaneous candidiasis | |
| Dose | 200 to 500 mg |
| Single Dose | 350 (350) |
| Frequency | 24 hourly |
| Route | PO,IV |
| Note: Maintenance, As Required | |
| Dose | 400 mg |
| Single Dose | 400 (400) |
| Frequency | As recommended. |
| Route | PO,IV |
| Note: Initially for Once |
Fluconazole Dosage for Neonatal
| Dose | 1 to 2 mg/kg |
| Single Dose | 1.5 (1.5) |
| Frequency | 24 hourly |
| Route | Slow IV |
| Note: - |
Fluconazole Dosage for Paedriatic
| Dose | 1 to 2 mg/kg |
| Single Dose | 1.5 (1.5) |
| Frequency | 24 hourly |
| Route | Slow IV |
| Note: - |
Brands
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