Ethinyloestradiol
Ethinyloestradiol Information

About Ethinyloestradiol

Ethinyloestradiol is estrogen (hormone). Ethinyloestradiol is used for replacement therapy in women who is deficient of hormone. Ethinyloestradiol is used to treat symptoms associated with menopause and conditions in which hormone levels are low. Ethinyloestradiol is also used to prevent osteoporosis (bone loss).

Indications

Ethinyloestradiol is primarily indicated in conditions like Breast cancer, Breast cancer (unlicensed indication), Dysfunctional uterine bleeding, Gonadal dysgenesis, Heriditary haemorrhagic telangiectasia, Hormone replacement for menopausal symptoms, Hormone replacement therapy, Menopausal symptoms, Oestrogen deficiency, Osteoporosis prophylaxis, Pre-ovulatory mucus, Prostatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Acne, Contraception, Endometriosis, Hirsutism, Menstruation disorders.

Contraindication

Ethinyloestradiol is contraindicated in conditions like Thromboembolism,Genital bleeding,Jaundice,Thrombophlebitis,Cerebrovascular disease,Hepatic carcinoma,Coronary artery disease,Estrogen-dependent cancer,Untreated endometriosis.

Side Effects

The severe or irreversible adverse effects of Ethinyloestradiol, which give rise to further complications include Impotence, Loss of libido, Gynacomastia, Chloasma, MI.Ethinyloestradiol produces potentially life-threatening effects which include Pulmonary embolism, Hypertension, Venous thromboembolism, Endometrial carcinoma, Endometrial hyperplasia, Cerebral thrombosis, Gall bladder disease, Liver tumors, Breast carcinoma, Venous thromboembolism, Coronary thrombosis. which are responsible for the discontinuation of Ethinyloestradiol therapy.The signs and symptoms that are produced after the acute overdosage of Ethinyloestradiol include Nausea, Vomiting, Coronary thrombosis, Uterine withdrawal bleeding.The symptomatic adverse reactions produced by Ethinyloestradiol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Vomiting, Weight gain, Fluid retention, Intermenstrual bleeding or spotting, Chloasma, Cholestatic Jaundice, Vaginal candidiasis, dizziness.

Warnings

High doses of ethinyloestradiol used in treatment of malignant disease should be used with caution in patients with cerebrovascular disorder, coronary artery disease or venous thromboembolism. It should be used with caution in children, because premature closure of epiphysis may occur resulting in inhibited linear growth and small stature.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.