Erythromycin
Erythromycin Information

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Erythromycin

medicine,pricing, side effects of Erythromycin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Erythromycin

Erythromycin is an intermediate spectrum macrolide antibiotic. It contains two deoxy sugars attached to a 14 atom macroyclic lactone ring. It was obtained in 1952 from Streptomyces erythreus. Erythromycin is effective against most gram positive and certain gram negative bacteria. Erythromycin is administered orally or topically. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Erythromycin is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.

Indications

Erythromycin is primarily indicated in conditions like Acne vulgaris, Alternative to penicillin in hypersensitive patients, Bacterial infections, Bone and joint infection, Breast cancer, Bronchitis, Endocarditis, Erythrasma, Eye infections, GI infections, Gonorrhoea, Heart failure, Lower respiratory tract infections, Lymphogranuloma venereum, Ophthalmia neonatorum, Otitis media, Pharyngitis, Pneumonia, Prophylaxis of bacterial endocarditis, Rosacea, Sexually transmitted infections, Sinusitis, Skin infections, Soft tissue infections, Supraventricular arrhythmias (particularly atrial fibrillation), Surgical prophylaxis, Syphilis, Upper respiratory tract infections, and can also be given in adjunctive therapy as an alternative drug of choice in Diphtheria, Early lyme disease.

Contraindication

Erythromycin is contraindicated in conditions like Hepatic dysfunction,Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Erythromycin, which give rise to further complications include Tinnitus, Pseudomembranous colitis, Urticaria, Hepatitis, Pancreatitis, Stevens johnson syndrome, Jaundice, Jaundice, Stevens johnson syndrome, Eosinophilia, Thrombophlebitis, Eosinophilia, Interstitial nephritis, Psychosis, Porphyria.Erythromycin produces potentially life-threatening effects which include Hepatotoxicity, QT prolongation, Severe skin reactions, Torsades de pointes. which are responsible for the discontinuation of Erythromycin therapy.The signs and symptoms that are produced after the acute overdosage of Erythromycin include Nausea, Severe vomiting, Diarrhea, Torsades de pointes, Hearing loss.The symptomatic adverse reactions produced by Erythromycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Anorexia, Fever, Skin reactions, Abdominal pain, Sweating, Maculopapular rash, Rashes, Pruritus, GI symptoms, Cramps, Elevation of liver enzymes, Hypersensitivity, Cholestasis, Reaction at injection site, dizziness.

Warnings

Erythromycin should be used only if clearly needed during pregnancy or lactation. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma). It should be used with caution in patients with any allergy, especially to antibiotics. Take appropriate measures if secondary infection occurs.

High Risk Groups

Drug should not be given to Cardiac / Hypertensive Patients, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Erythromycin Dosage for Adults

Dose 0.5 to 1 g
Single Dose 0.75 (0.75)
Frequency 6 hourly
Route IV
Dose 250 to 500 mg
Single Dose 380 (375)
Frequency 6 hourly
Route PO
Note: For 7-14 days.

Erythromycin Dosage for Neonatal

Dose 7.812 to 15.625 mg/kg
Single Dose 12 (11.7185)
Frequency 6 hourly
Route Oral

Erythromycin Dosage for Paedriatic

Dose 18.75 mg/kg
Single Dose 19 (18.75)
Frequency 4 hourly
Route Oral

Brands


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