Ergometrine (Maleate)
Ergometrine (Maleate) Information

About Ergometrine (Maleate)

Ergometrine (Maleate) is a derivative of ergot (fungus). It produces contraction of uterine muscle and used after delivery of baby to prevent or reduce maternal haemorrhage.

Indications

Ergometrine (Maleate) is primarily indicated in conditions like Bleeding caused by uterine atony, Migraine, Postabrortal haemorrhage, Postpartum haemorrhage, Prevention and treatment of haemorrhage due to incomplete abortion, Routine management of the 3rd stage of labour, Uterine subinvolution, and can also be given in adjunctive therapy as an alternative drug of choice in Uterine atony.

Contraindication

Ergometrine (Maleate) is contraindicated in conditions like Hypertension in pregnancy,Renal diseases,Liver diseases,Labor induction,Heart disease,Threatened spontaneous abortion,Arteriovenous shunt.

Side Effects

The severe or irreversible adverse effects of Ergometrine (Maleate), which give rise to further complications include Vascular complications, Ischemia, Gangrene.Ergometrine (Maleate) produces potentially life-threatening effects which include Coma, Seizures, Nausea, Vomiting, Hypertension, Hypotension, Diarrhea, Cold extremities, Severe thirst, Confusion. which are responsible for the discontinuation of Ergometrine (Maleate) therapy.The signs and symptoms that are produced after the acute overdosage of Ergometrine (Maleate) include Nausea, Vomiting, Seizures, Angina, Confusion, Unconsciousness, Palpitations, Dizziness, Hypertension, Gangrene, Dyspnea, Vasoconstriction of the extremities.The symptomatic adverse reactions produced by Ergometrine (Maleate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Palpitation, Tinnitus, Abdominal pain, VertigoX, Chest pain, Angina, Shortening of breath, Pulmonary edema, dizziness.

Warnings

Ergometrine should not be used for the induction of labor or during the first stage of labor. Its use should be avoided in patients with eclampsia. In case of any kind of infection or illness check with your doctor before taking Ergonovine since sensitivity to ergonovine's effects may increase.It should be used with caution in patient with impaired pulmonary function, sepsis, renal or hepatic disease and in patients with porphyria. Patient should be advised not to drive or use machines while receiving ergonovine.In case of any kind of infection or illness check with your doctor before taking Ergonovine since sensitivity to ergonovine's effects may increase.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.