Eletriptan
Eletriptan Information

About Eletriptan

Eletriptan is a selective serotonin (5HT-1) agonist. Eletriptan is given orally in the treatment of acute migraine attacks. It may be used during the established headache phase of an attack and is the preferred treatment in those who fail to respond to conventiaonal analgesics.

Indications

Eletriptan is primarily indicated in conditions like Long-term treatment of reflux oesophagitis, Treatment of acute migraine attacks.

Contraindication

Eletriptan is contraindicated in conditions like Peripheral vascular disease,Uncontrolled hypertension,Severe hypertension associated with renal disease,Chronic intractable hypoglycaemia.

Side Effects

The symptomatic adverse reactions produced by Eletriptan are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Ataxia, Nausea, Anorexia, Myalgia, Dyspnea, Restlessness, Insomnia, Tinnitus, Abdominal pain, Dry mouth, Confusion, Pruritus, Bradycardia, Pharyngitis, Hallucination, Dyspepsia, Hypotension, Transient increase in blood pressure, Depression, Tremor, Asthenia, Arthralgia, Glossitis, Edema, Rhinitis, Euphoria, Chest pain, Agitation, Wheezing, Muscle pain, Increased urinary frequency, Dry mouth, Confusion, dyspepsia, Ataxia.

Warnings

5HT1 agonists (e.g Eletriptan) should be used with caution in conditions which predispose to coronary artery disease (pre-existing cardiac disease), pregnancy and breast-feeding. 5HT1 agonists are recommended as monotherapy and should not be taken concurrently with other acute migraine therapies. Little information is available on the use of these drugs in the elderly (over 65 year). Caution is also required in mild or moderate hepatic impairment and renal impairment; not to be taken until 24 hours after stopping ergotamine-type prepration (ergotamine-type prepration not to be taken until 6 hours after Eletriptan)

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.