Domperidone
Domperidone Information

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Domperidone

medicine,pricing, side effects of Domperidone medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Domperidone

Domperidone is a dopamine blocking agent. Domperidone is antiemetic agent. Domperidone is also used to treat nausea and vomiting induced by cancer chemotherapy.

Indications

Domperidone is primarily indicated in conditions like Acute nausea and vomiting, Delayed gastric emptying, Dyspepsia, Functional dyspepsia, Gastric distension pain due to pressure on the stomach, Gastro-oesophageal reflux disease, Nausea and vomiting, Nausea and vomiting (chemotherapy induced), Nausea and vomiting (L-dopa induced), Non-ulcer dyspepsia, Reflux oesophagitis, and can also be given in adjunctive therapy as an alternative drug of choice in Cytotoxic chemotherapy, Heart burn, Lactation.

Contraindication

Domperidone is contraindicated in conditions like Allergy,Hepatic impairment,Serious resistant GI mycoses.

Side Effects

The severe or irreversible adverse effects of Domperidone, which give rise to further complications include Tardive dyskinesia, Parkinsonism, Extrapyramidal dystonic reactions.Domperidone produces potentially life-threatening effects which include Seizures, Dysrhythmias. which are responsible for the discontinuation of Domperidone therapy.The signs and symptoms that are produced after the acute overdosage of Domperidone include Convulsions, Coma, GI disturbances, Extrapyramidal effects.The symptomatic adverse reactions produced by Domperidone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Thirst, Headache, Drowsiness, Diarrhea, Anxiety, Restlessness, Insomnia, Nervousness, Skin rashes, Dry mouth, Itching, Galactorrhea, Breast enlargement, Soreness, Hyperprolactinemia, nervousness, Reduced libido.

Warnings

Domperidone should be used with great caution if given intravaneously, because of the risk of arrhythmias, especially to patients predisposed to cardiac arrhythmias or hypokalaemia.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Domperidone Dosage for Adults

Dose 10 to 20 mg
Single Dose 15 (15)
Frequency 6 hourly
Route PO
Note: 15-30 minutes before meal. It can be used for maximum 12 weeks.
Dose 30 to 60 mg
Single Dose 45 (45)
Frequency 6 hourly
Route Suppository

Domperidone Dosage for Neonatal

Dose 0.2 to 0.4 mg/kg
Single Dose 0.3 (0.3)
Frequency 8 hourly
Route Oral
Note: -

Domperidone Dosage for Paedriatic

Dose 250 to 0.4 ug/kg
Single Dose 130 (125.2)
Frequency 8 hourly
Route Oral
Note: 15-30 minutes before meal. It can be used for maximum 12 weeks. To a total daily dose of 80mg.
Dose 30 to 120 mg
Single Dose 75 (75)
Frequency 8 hourly
Route Suppository

Brands


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