Dexamethasone
Dexamethasone Information

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Dexamethasone

medicine,pricing, side effects of Dexamethasone medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Dexamethasone

Chemically Dexamethasone is 9-Fluoro-11ß, 17, 21-trihydroxy-16a-methylpregna-1, 4-diene-3, -20-dione. Dexamethasone is a corticosteroid. It reduces swelling and inflammation. Dexamethasone is used in different conditions such as skin diseases, allergic conditions, breathing problems, cancer, blood disorders, eye diseases and in arthritis. Dexamethasone is also used to treat nausea and vomitting produced by cancer chemotherapy;.

Indications

Dexamethasone is primarily indicated in conditions like Adrenocortical insufficiency, Anorexia in palliative care, Brain tumors, Cerebral oedema, Congenital adrenal hyperplasia, Dyspnoea, Dyspnoea in palliative care, Headache due to raised intracranial pressure in palliative care, Nausea and vomiting (chemotherapy induced), Pain due to nerve compression in palliative care, Palliative surgery., Raised intracranial pressure, Respiratory distress syndrome, Shock, Suppression of inflammatory and allergic disorders, and can also be given in adjunctive therapy as an alternative drug of choice in Asthma, Blood disorders, Connective tissue diseases, GI diseases, Liver diseases, Malignancy, Ocular diseases, osteoarthiritis of superficial joints, Osteoarthritis, Renal diseases.

Contraindication

Dexamethasone is contraindicated in conditions like Diabetes mellitus,Hypertension,Psychosis,Osteoporosis,GI ulceration,Infections,Renal insufficiency.

Side Effects

The severe or irreversible adverse effects of Dexamethasone, which give rise to further complications include Glaucoma, Peptic ulceration, Myopathy, Osteoporosis, Posterior subcapsular cataract, Growth retardation, Aseptic bone necrosis, Ocular hypertension, Subcapsular cataract, Pancreatic disturbance, Cushing like features, Oedema, Retinal detachment, Moon face, Truncal obesity, Negative calcium balance.Dexamethasone produces potentially life-threatening effects which include Collapse, Suppression of hypothalamus-pituitary-adrenal axis. which are responsible for the discontinuation of Dexamethasone therapy.The symptomatic adverse reactions produced by Dexamethasone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Insomnia, Nervousness, Nocturia, Increased appetite, Obesity, Facial rounding, Fragility of skin, Euphoria, Glucose intolerance, nervousness, Nervousness, adrenal suppression, protein catabolism, lipid metabolism.

Warnings

Dexamethasone should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoprosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid cause growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3 months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred. Dose adjustment required in patient with renal

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Dexamethasone Dosage for Adults

Dose 0.5 to 24 mg
Single Dose 12 (12.25)
Frequency As recommended.
Route IV,IM
Note: Once in Weeks
Dose 0.1 %
Single Dose 0.1 (0.1)
Frequency As recommended.
Route Ophthalmic
Note: As Required.To be given as drops.
Dose 0.5 to 10 mg
Single Dose 5.2 (5.25)
Frequency 24 hourly
Route PO

Dexamethasone Dosage for Neonatal

Dose 0.2 mg/kg
Single Dose 0.2 (0.2)
Frequency 8 hourly
Route Intramuscular
Dose 0.2 mg/kg
Single Dose 0.2 (0.2)
Frequency 8 hourly
Route Intravenous
Dose 0.2 mg/kg
Single Dose 0.2 (0.2)
Frequency 8 hourly
Route oral

Dexamethasone Dosage for Paedriatic

Dose 20.8 mg
Single Dose 21 (20.8)
Frequency 6 hourly
Route Intra Venous
Note: Initial dose followed by 3.3mg till 8th day then by daily reduction of 1.7mg.For 35 kg and over
Dose 20.8 mg
Single Dose 21 (20.8)
Frequency As recommended.
Route IV
Note: Initial dose . The follow up is same This dose is for children below 35 kg.
Dose 1 %
Single Dose 1 (1)
Frequency 6 hourly
Route Opthalmic
Note: 1 to 2 drops
Dose 0.01 to 0.1 mg/kg
Single Dose 0.055 (0.055)
Frequency 24 hourly
Route Oral
Note: daily

Brands

1- ADRENAAL - 4mg/ml MG

2- ALDRON - 4mg/ml MG

3- ALDRON - 0.5mg MG

4- AMGYDEX - 0.1%w/v MG

5- AMGYDEX - 0.1%w/w MG

6- ATNESON - 4mg/ml MG

7- BAYCUTEN-N - 0.4%w/w MG

8- BAYCUTEN-N - 0.4%w/w MG

9- BECLOTRIM - 0.4%w/w MG

10- BINADEX - 0.1%w/v MG

11- BRACIN-D - 0.1%w/v MG

12- BRADEX - 0.1%w/v MG

13- BROMYCIN-D - 0.1%w/v MG

14- CARPILLA - 0.1gm MG

15- CECIDRON - 4mg/ml MG

16- CHLORDEX - 0.1%w/v MG

17- CINDEX - 0.1%w/v MG

18- CIPOTIC-D - 0.1%w/v MG

19- D CORT - 4mg/ml MG

20- D SONE - 4mg/ml MG

21- D.DRON - 4mg/ml MG

22- DANADEX - 4mg/ml MG

23- DANADEX - 4mg/ml MG

24- DECACHLOR - 0.1%w/v MG

25- DECADRON - 4mg/ml MG

26- DECADRON - 4mg/ml MG

27- DELTASALONE - 4mg/ml MG

28- DEXA N - 0.1%w/w MG

29- DEXACHLOR - 0.1%w/v MG

30- DEXACOR - 1mg MG

31- DEXACOR - 0 MG

32- DEXACORT - 0.5mg MG

33- DEXADRIN - 4mg/ml MG

34- DEXADRIN - 4mg/ml MG

35- DEXADRIN - 0.5mg MG

36- DEXADRON - 0.5mg MG

37- DEXADRON T - 0.1%w/v MG

38- DEXAFLOX - 0.1%w/v MG

39- DEXAMED - 4mg/ml MG

40- DEXAMEDRON - 4mg/ml MG

41- DEXAMEDRON - 4mg/ml MG

42- DEXAMEK - 4mg/ml MG

43- DEXAMEK - 0.5mg MG

44- DEXAMETHASONE - 0.5mg MG

45- DEXAMETHASONE - 0.5mg MG

46- DEXAMETHASONE - 4mg/ml MG

47- DEXAMETHASONE - 0.5mg MG

48- DEXAMETHASONE - 0.5mg MG

49- DEXAMETHASONE - 4mg/ml MG

50- DEXAMETHASONE - 0.5mg MG

51- DEXAMETHASONE - 4mg/ml MG

52- DEXAMETHASONE - 2mg/ml MG

53- DEXAMETHASONE - 4mg/ml MG

54- DEXAMETHASONE - 0.5mg MG

55- DEXAMETHASONE - 0.5mg MG

56- DEXAMETHASONE - 4mg/ml MG

57- DEXAMETHASONE - 4mg/ml MG

58- DEXAMETHASONE - 4mg/ml MG

59- DEXAMETHASONE - 0.5mg MG

60- DEXAMETHASONE - 4mg/ml MG

61- DEXAMETHASONE - 4mg/ml MG

62- DEXAMETHASONE - 4mg/ml MG

63- DEXAMETHASONE - 4mg/ml MG

64- DEXAMETHASONE - 4mg/ml MG

65- DEXAMETHASONE - 0.5mg MG

66- DEXAMEX - 0.1%w/v MG

67- DEXAMEX - 20mg MG

68- DEXAMEX - 100mg MG

69- DEXAMEX - 4mg/ml MG

70- DEXAMIN-N - 0.1%w/w MG

71- DEXAMIN-N - 0.1%w/w MG

72- DEXAROID - 4mg/ml MG

73- DEXATEX - 0.5mg MG

74- DEXATOB - 0.1%w/v MG

75- DEXCIP - 0 MG

76- DEXER - 0.1%w/w MG

77- DEXIMOX - 1mg MG

78- DEXOFLOX - 0.1%w/v MG

79- DEXONE - 0.5mg MG

80- DEXONE - 0.5mg MG

81- DEXONIL - 0 MG

82- DEXOPTIC - 0.1%w/v MG

83- DEXOPTIC - 0.1%w/w MG

84- DEXOPTIC-C - 0.1%w/v MG

85- DEXSUL - 0 MG

86- DICON EYE DROPS - 0.1%w/v MG

87- DICON-N - 0.1%w/v MG

88- DOSACHLOR - 0.1%w/v MG

89- EPHADEX N - 0.1%w/w MG

90- EPODEX-N - 0.1%w/w MG

91- ERODEX-N - 3500IU/g MG

92- EYEBRADEX - 0.1%w/v MG

93- FAIRSONE - 0.5mg MG

94- FLADEXON - 0.5mg MG

95- FLUOROBIOPTAL - 0.2%w/v MG

96- FOCALIN - 0.1%w/v MG

97- FORTECORTIN - 4mg/ml MG

98- FRADEX - 0.1%w/v MG

99- HAMAZONE - 0.5mg MG

100- IRZAMETHASONE - 4mg/ml MG

101- IRZAMETHASONE - 0.5mg MG

102- KANADEX - 0.5mg MG

103- KANADEX-N - 0.1%w/w MG

104- KENIDEX-N - 0.1gm MG

105- KLOZEN - 0.1%w/v MG

106- MAXIDEX - 0.1%w/v MG

107- MAXITROL DROPS - 0.1%w/v MG

108- MAXITROL OINTMENT - 0.1%w/w MG

109- MEBRADEX - 0.1%w/v MG

110- MEDIDEX - 0.1%w/v MG

111- MEDIDEX-C - 0.1%w/v MG

112- MEDIOFLOX-D - 0 MG

113- MEDITROL - 0.1%w/v MG

114- MERRYSONE - 4mg MG

115- MERRYSONE - 4mg MG

116- METAAREX - 0.1%w/v MG

117- METADEX - 0 MG

118- METHADEX - 0 MG

119- METHADEX N - 0 MG

120- METHADO - 0.04%w/w MG

121- METHASONE - 0.1%w/v MG

122- METHASUL - 0.1%w/v MG

123- METHAZONE - 0.5mg MG

124- METHOX - 4mg/ml MG

125- MYDEX - 0.1%w/v MG

126- MYRET - 0.1%w/v MG

127- NEODEX - 0.1%w/w MG

128- NEUDEX - 4mg/ml MG

129- OBRADEX - 0.1%w/v MG

130- OCUDEX - 0.1%w/v MG

131- OCUTOB-DEX - 0.1%w/v MG

132- OCUTODEX - 0 MG

133- OCUTROL - 0.1%w/v MG

134- OPHTH-DEX - 0.1%w/v MG

135- OPHTH-NEODEX - 0.1%w/v MG

136- OPHTH-TOBRA-D - 0.1%w/v MG

137- OPHTH-TOBRA-D - 0.1%w/w MG

138- OPTADEX - 0.1%w/v MG

139- OPTADEX-N - 0.1%w/v MG

140- ORADEXON - 4mg/ml MG

141- ORADEXON - 4mg/ml MG

142- ORADEXON - 0.5mg MG

143- ORADEXON - 0.5mg MG

144- ORBATROL - 0.1%w/v MG

145- ORBATROL - 0.1%w/w MG

146- ORCYDEX - 0 MG

147- OXCIN-D - 0.1%w/v MG

148- PHESONE - 0.5mg MG

149- PLIDAXAN - 0 MG

150- POLDEC - 00 MG

151- POLYDEX - 0.1%w/v MG

152- POLYTROL - 0.1%w/v MG

153- PRIMADEX N - 0.1%w/w MG

154- QUINODEX - 0.1% MG

155- RECADRON - 0.5mg MG

156- RECADRON - 0.5mg MG

157- SANTIROL - 0.1%w/v MG

158- SANTODEX - 0.1%w/v MG

159- SANTODEX - 0.1%w/w MG

160- SHIRODEX - 0.5mg MG

161- SHIRODEX - 0.5mg MG

162- SPERSADEX - 0.1%w/v MG

163- SPERSADEX COMPOUND - 0.1%w/v MG

164- SPERSADEXOLINE - 0.1%w/v MG

165- STERIBIOL - 0.1%w/v MG

166- STERIDEX - 0.1%w/v MG

167- SULPHOFAX - 0 MG

168- SULPHOFAX - 0 MG

169- TOBCYDEX - 0.1% MG

170- TOBRA-D - 0.1%w/v MG

171- TOBRACIN-D - 0.1%w/v MG

172- TOBRADEX - 0.1%w/v MG

173- TOBRADEX - 0.1%w/w MG

174- TOBRAMET - 0.1%w/v MG

175- TODEX - 0.1%w/v MG

176- TRANCE - 0.1%w/v MG

177- UNISONE - 0.5mg MG

178- VEGADEX - 0 MG

179- VEGADEX C - 0.1%w/v MG

180- VEGATOB - 0 MG

181- Z-DEX - 4mg/ml MG

182- ZOMADEX-N - 1mg MG


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