Cloxacillin
Cloxacillin Information
Find all the information of Cloxacillin medicine and drugs available in Pakistan. Read the pricing, side effects, usage, instructions and dosage of Cloxacillin by .
Cloxacillin
medicine,pricing, side effects of Cloxacillin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.About Cloxacillin
Cloxacillin is an isoxazolyl penicillin. Penicillin is derived directly or indirectly from strains of fungi of the genus Penicillium and other soil inhabiting fungi grown on special culture media. The structure of penicillin consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain. its use is limited to treatment of penicillinase-producing Staphylococcus aureus infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Cloxacillin (Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Indications
Cloxacillin is primarily indicated in conditions like Bacterial infections, Bone and joint infection, Cystitis, Endocarditis, Enterocolitis, Meningitis associated with spina bifida, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections.
Contraindication
Cloxacillin is contraindicated in conditions like Hypersensitivity.
Side Effects
The severe or irreversible adverse effects of Cloxacillin, which give rise to further complications include Cholestatic jaundice, Hemolytic anemia, Blood dyscrasias, Seizures, Interstitial nephritis, Cholestasis, Neurotoxicity.Cloxacillin produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis. which are responsible for the discontinuation of Cloxacillin therapy.The signs and symptoms that are produced after the acute overdosage of Cloxacillin include Vomiting, Diarrhea, GI disturbances, Abdominal discomfort.The symptomatic adverse reactions produced by Cloxacillin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Rashes, Phlebitis, Glossitis, StomatitisX, Nausea and vomiting, GI disturbance, Hyperthermia.
Warnings
Cloxacillin should be used with caution in patients with any other illnesses or any allergy especially to penicillin or other antibiotics.This medication should be used only if clearly needed during pregnancy or lactation.
High Risk Groups
Drug should not be given to patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Dosage
Cloxacillin Dosage for Adults
| Dose | 250 mg |
| Single Dose | 250 (250) |
| Frequency | 6 hourly |
| Route | IM |
| Dose | 500 mg |
| Single Dose | 500 (500) |
| Frequency | 24 hourly |
| Route | Intra Peritoneal |
| Dose | 500 mg |
| Single Dose | 500 (500) |
| Frequency | 6 hourly |
| Route | IV (slow) |
| Note: Over 3-4 min. | |
| Dose | 500 mg |
| Single Dose | 500 (500) |
| Frequency | 6 hourly |
| Route | PO |
Cloxacillin Dosage for Neonatal
| Dose | 7.812 to 15.625 mg/kg |
| Single Dose | 12 (11.7185) |
| Frequency | 6 hourly |
| Route | oral |
| Dose | 7.812 to 15.625 mg/kg |
| Single Dose | 12 (11.7185) |
| Frequency | 6 hourly |
| Route | Slow intravenous |
Cloxacillin Dosage for Paedriatic
| Dose | 12.5 to 25 mg/kg |
| Single Dose | 19 (18.75) |
| Frequency | 6 hourly |
| Route | Oral |
| Note: - | |
| Dose | 12.5 to 25 mg/kg |
| Single Dose | 19 (18.75) |
| Frequency | 6 hourly |
| Route | Slow IV |
| Note: - |
Brands
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