Clopamide
Clopamide Information

About Clopamide

Clopamide is a diuretic reduces the absorption of electrolytes from renal tubule. It increases the urination. Clopamide is used in hypertention to lower the high blood pressure and to treat edema associated with heart failure.

Indications

Clopamide is primarily indicated in conditions like Congestive heart failure, Hepatic disease, Mild to moderate hypertension.

Contraindication

Clopamide is contraindicated in conditions like Gout,Maturity onset diabetes,Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Clopamide, which give rise to further complications include Hypokalemia, Hyperglycemia, Precipitation of gout, Hyperglycemia.Clopamide produces potentially life-threatening effects which include Coronary insufficiency, Decreased BP. which are responsible for the discontinuation of Clopamide therapy.The symptomatic adverse reactions produced by Clopamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Gout, Renal failure, Hepatic failure.

Warnings

The drug should be used with extreme caution in diabetic patients because clopamide can worsen diabetic control, raising blood sugar level and may precipitate gout. It should be used with caution in combination with other antihypertensive drugs such as thiazide and loop diuretics, as it increases the urinary excretion of potassium and can cause hypokalemia, potassium supplements are used to treat hypokalemia.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.